Domestic use of hypochlorite bleach, atopic sensitization, and respiratory symptoms in adults  Jan-Paul Zock, PhD, Estel Plana, MSc, Josep M. Antó, MD, Geza Benke, PhD, Paul D. Blanc, MD, Aurelia Carosso, MD, Anna Dahlman-Höglund, PhD, Joachim Heinrich, PhD, Deborah Jarvis, MD, Hans Kromhout, PhD, Linnéa Lillienberg, PhD, Maria C. Mirabelli, PhD, Dan Norbäck, PhD, Mario Olivieri, MD, Michela Ponzio, PhD, Katja Radon, PhD, Argo Soon, MD, Marc van Sprundel, MD, Jordi Sunyer, MD, Cecilie Svanes, MD, Kjell Torén, MD, Giuseppe Verlato, MD, Simona Villani, PhD, Manolis Kogevinas, MD  Journal of Allergy and Clinical Immunology  Volume 124, Issue 4, Pages 731-738.e1 (October 2009) DOI: 10.1016/j.jaci.2009.06.007 Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Association between the use of bleach (ever) and atopy by country. OR and 95% CI, adjusted within countries for study center, sex, age, smoking status, family history of allergic disease, and number of siblings, are shown. The size of each square is proportional to the reciprocal of the variance of the estimate for the country. The diamond indicates 95% CI of the combined OR from the model, with country as the random effect (P = .20, test for heterogeneity). Countries are ranked from high (top) to low (bottom) by the frequency of bleach use (percentages indicated between brackets). UK, United Kingdom. Journal of Allergy and Clinical Immunology 2009 124, 731-738.e1DOI: (10.1016/j.jaci.2009.06.007) Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions