Inhibition of human sperm function and mouse fertilization in vitro by an antibody against cation channel of sperm 1: the contraceptive potential of its.

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Inhibition of human sperm function and mouse fertilization in vitro by an antibody against cation channel of sperm 1: the contraceptive potential of its transmembrane domains and pore region Honggang Li, Ph.D., Xiaofang Ding, Ph.D., Huangtao Guan, B.A., Chengliang Xiong, M.D Fertility and Sterility Volume 92, Issue 3, Pages 1141-1146 (September 2009) DOI: 10.1016/j.fertnstert.2008.07.1751 Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions

Figure 1 The hyperactivated sperm of the blank control (B), normal rabbit IgG control (C), and H-300-treated group (D). Each data point represents an individual sperm cell. The boxes define regions containing hyperactivated sperm delimited by the 90th percentile VCL and 10th percentile STR values from the noncapacitated sperm (A). Fertility and Sterility 2009 92, 1141-1146DOI: (10.1016/j.fertnstert.2008.07.1751) Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions

Figure 2 In vitro fertilization with mouse sperm from cauda epididymis pretreated with H-300 (B) or normal rabbit IgG control, (A). Scale bar represents 100 μM. Fertility and Sterility 2009 92, 1141-1146DOI: (10.1016/j.fertnstert.2008.07.1751) Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions