Figure 6 Imaging methods used to study Parkinson disease

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Figure 6 Imaging methods used to study Parkinson disease Part c is adapted with permission from Reiter, E. et al. Dorsolateral nigral hyperintensity on 3.0T susceptibility-weighted imaging in neurodegenerative Parkinsonism. Mov Disord. 30, 1068–1076 (2015), Wiley. Part d is adapted with permission from Ohtsuka, C. et al. Changes in substantia nigra and locus coeruleus in patients with early-stage Parkinson’s disease using neuromelanin-sensitive MR imaging. Neurosci. Lett. 541, 93–98 (2013), Elsevier. Part e is adapted with permission from Schmidauer, C. et al. Transcranial ultrasound shows nigral hypoechogenicity in restless legs syndrome. Ann. Neurol. 58, 630–634 (2005), Wiley Poewe, W. et al. (2017) Parkinson disease Nat. Rev. Dis. Primers doi:10.1038/nrdp.2017.13