Welcome To The Centre for Applied Genomics

Quotable Quotes "The scientist is not a person who gives the right answers; he's one who asks the right questions. ~ Claude Lévi-Strauss

This week at TCAG Lab meeting "Explosive factors and exciting mechanisms controlling allele preference in imprinting and gene expression" Given by Layla Parker-Katiraee Wednesday, Nov 14, 1:30 PM 14th Floor Conference Room

Oligo synthesis 17,946 oligos synthesized since January 1, 2006 up to 120 bases conventional & modified free delivery to downtown Toronto New lower prices! 40 nmole 200 nmole 1000 nmole Cost per base $0.59 $0.89 $1.89 Cartridge purification $15.00 $15.00 $30.00 17,946 oligos synthesized since January 1, 2006

DNA Sequencing 146,750 reads since January 1, 2006 plasmids, PCR products BAC ends, other genomic clones mutation screening Solexa next-generation sequencing 146,750 reads since January 1, 2006

Now available! Ultra-high throughput sequencing with the Illumina Genome Analyzer

Biobanking 7,182 cell lines handled since January 1, 2006 DNA preparation cell line transformation DNA, white cell, and cell line banking other cells on request 7,182 cell lines handled since January 1, 2006

Genome resources 5,218 clones prepared since January 1, 2006 cDNA libraries genomic clone libraries whole-genome DNA amplification project support – database queries, annotation, probe selection 5,218 clones prepared since January 1, 2006

Genetic analysis > 2.5 billion genotypes since January 1, 2006 TaqMan, SNaPshot, microsatellites Illumina GoldenGate and Infinium Illumina gene expression analysis Real time PCR (qPCR) Mouse genotyping and linkage analysis > 2.5 billion genotypes since January 1, 2006

Microarray Affymetrix Human SNP Array 6.0 now available! Affymetrix expression and exon arrays SNP GeneChips and MegAllele Agilent oligo arrays Affymetrix Human SNP Array 6.0 now available! More information and pricing is available on our website. 4,800 arrays processed since January 1, 2006

Statistical analysis 12,264 hours of project support study design consultation power analysis analysis of genetic, microarray, genomic copy number, clinical, and proteomic data 12,264 hours of project support since January 1, 2006

Cytogenomics 707 FISH, 1,769 probes labeled since January 1, 2006 karyotyping FISH and sequential G-to-FISH mapping fluorescent probe labeling spectral karyotping (SKY) breakpoint mapping array-CGH 707 FISH, 1,769 probes labeled since January 1, 2006

Enabling High Impact Research

970 facility users worldwide (28 countries) Argentina Australia Belgium Brazil Canada China Costa Rica Czech Republic England Finland France Germany Hong Kong India Israel Italy Japan The Netherlands Peru Scotland Singapore Spain Sweden Switzerland Taiwan Turkey USA

22 Genome Canada projects supported

The Friendly Faces of TCAG!

SickKids Foundation CIHR Canadian Genetic Diseases Network Genome Canada / OGI McLaughlin Centre for Molecular Medicine CFI / Ontario