Importins/Karyopherins Meet Nucleoporins

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Importins/Karyopherins Meet Nucleoporins E.C Hurt Cell Volume 84, Issue 4, Pages 509-515 (February 1996) DOI: 10.1016/S0092-8674(00)81026-0

Figure 1 A Model of Interaction among Components Involved in Nucleocytoplasmic Transport It is not clear whether the drawn interactions occur simultaneously. NLS, karyophilic protein with a nuclear localization sequence; α, karyopherin-α/importin-α; β, karyopherin-β/importin-β; RanGDP, Ran/TC4 in its GDP-bound form; pp15, nuclear import factor pp15; nucleoporin with Ran-binding domain (Ran-BD), FXFG repeat sequences (FXFG), and an NPC-binding domain (NPC-BD). For further explanations, see text. Cell 1996 84, 509-515DOI: (10.1016/S0092-8674(00)81026-0)