Misleading Bioinformatics Mistakes, Biases, Mis-Interpretations and how to avoid them Festival of Genomics 2017.

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Presentation transcript:

Misleading Bioinformatics Mistakes, Biases, Mis-Interpretations and how to avoid them Festival of Genomics 2017

  Experimental Design and Planning Library Preparation Sample Tracking Sequencing Quantitation Comparison Statistics Functional Analysis Results

Software / Statistics Selection Validate Check your samples, effects and expectations Explore Understand your data before starting any analysis Normalise If problems or biases exist, fix or remove them Analyse Only analyse once you have a specific question to answer Backtrack Don’t trust your hits – work back through the pipeline Question Am I making the correct interpretation of my hits Software / Statistics Selection

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