Retinoids Run Rampant Neuron

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Retinoids Run Rampant Neuron Bruce Appel, Judith S Eisen Neuron Volume 40, Issue 3, Pages 461-464 (October 2003) DOI: 10.1016/S0896-6273(03)00688-3

Figure 1 Opposing RA and FGF Signaling Regulates Onset of Neurogenesis and Ventral Neural Patterning Schematic represents a dorsal view of the caudal region of a developing chick embryo. Right side depicts early stages of neural development. Open circles are self-renewing stem cells, gray circles are neuroectodermal cells, and black circles are neurons. Red circles represent a putative clone, where descendents that occupy the stem zone remain together as the zone progresses posteriorly (arrows) and those that enter the transition zone are distributed along the RC axis (see Mathis et al., 2001). Onset of neurogenesis is coincident with somite formation. Left side depicts signaling interactions described in text. Neuron 2003 40, 461-464DOI: (10.1016/S0896-6273(03)00688-3)

Figure 2 RA Signaling Regulates Many Phases of MN Differentiation Neuron 2003 40, 461-464DOI: (10.1016/S0896-6273(03)00688-3)