A Sympathetic View on Fat by Leptin

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A Sympathetic View on Fat by Leptin Luis Varela, Tamas L. Horvath Cell Volume 163, Issue 1, Pages 26-27 (September 2015) DOI: 10.1016/j.cell.2015.09.016 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 1 Post-ganglionic Axonal Projections Innervate Fat Depots Stimuli from the different areas of the brain reach fat depots. Zeng et al. provide evidence that the WAT is innervated by axonal projections from ganglionic neurons. Optogenetic stimulation and genetic, chemical, or physical inhibition of these axons at the post-ganglionic level can mimic or block leptin effects on lipolysis in WAT, respectively. Cell 2015 163, 26-27DOI: (10.1016/j.cell.2015.09.016) Copyright © 2015 Elsevier Inc. Terms and Conditions