Chemical mediators in atopic dermatitis: Involvement of leukotriene B4 released by a type I allergic reaction in the pathogenesis of atopic dermatitis

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Presentation transcript:

Chemical mediators in atopic dermatitis: Involvement of leukotriene B4 released by a type I allergic reaction in the pathogenesis of atopic dermatitis Osamu Koro, MD, Kiyoshi Furutani, MD, Michihiro Hide, MD, PhD, Satoru Yamada, MD, PhD, Shoso Yamamoto, MD, PhD Journal of Allergy and Clinical Immunology Volume 103, Issue 4, Pages 663-670 (April 1999) DOI: 10.1016/S0091-6749(99)70240-X Copyright © 1999 Mosby, Inc. Terms and Conditions

Fig. 1 A, NCA in fractions of HPLC. Reaction mixture of the in vitro study was fractionated by reversed-phase HPLC. NCA is expressed by a chemotactic index (number of neutrophils infiltrated by sample/number of neutrophils infiltrated by corresponding buffer). B, LTB4 in the fractions of HPLC. LTB4 is expressed as picograms per fraction. Journal of Allergy and Clinical Immunology 1999 103, 663-670DOI: (10.1016/S0091-6749(99)70240-X) Copyright © 1999 Mosby, Inc. Terms and Conditions