First estimates of the global and regional incidence of neonatal herpes infection Dr Katharine J Looker, PhD, Amalia S Magaret, PhD, Margaret T May, PhD,

Slides:

Advertisements

Similar presentations

Volume 353, Issue 9155, Pages (March 1999)

Advertisements

Preventive malaria treatment for contacts of patients with Ebola virus disease in the context of the west Africa 2014–15 Ebola virus disease response:

Levels and trends in contraceptive prevalence, unmet need, and demand for family planning for 29 states and union territories in India: a modelling study.

Trends in Coronary Heart Disease Epidemiology in India

The benefits and harms of breast cancer screening

Two Classic Lyrics Joined by a Contemporary Tune—Environmental Pro-Carcinogen Exposure and Genetic Susceptibility in Lung Cancer Risk Ping Yang, MD,

Prediction of cervical cancer incidence in England, UK, up to 2040, under four scenarios: a modelling study Alejandra Castanon, MD, Rebecca Landy, PhD,

Ending preventable maternal deaths: the time is now

Socioeconomic inequality in neonatal mortality in countries of low and middle income: a multicountry analysis Britt McKinnon, MSc, Sam Harper, PhD, Prof.

Contribution of alcohol use disorders to the burden of dementia in France 2008–13: a nationwide retrospective cohort study Michaël Schwarzinger, MD,

Prevalence of symptoms of vaginal fistula in 19 sub-Saharan Africa countries: a meta- analysis of national household survey data Mathieu Maheu-Giroux,

Active surveillance for rheumatic heart disease in endemic regions: a systematic review and meta-analysis of prevalence among children and adolescents

Annual rates of decline in child, maternal, HIV, and tuberculosis mortality across 109 countries of low and middle income from 1990 to 2013: an assessment.

Early antenatal care visit: a systematic analysis of regional and global levels and trends of coverage from 1990 to 2013 Ann-Beth Moller, MPH, Max Petzold,

Age-related trends in utilization and outcome of open and endovascular repair for abdominal aortic aneurysm in the United States, Margaret.

Socioeconomic status and non-communicable disease behavioural risk factors in low- income and lower-middle-income countries: a systematic review Luke.

Global, regional, and subregional trends in unintended pregnancy and its outcomes from 1990 to 2014: estimates from a Bayesian hierarchical model Jonathan.

Nicola Low, Joost H Smid The Lancet Public Health

Burden of childhood tuberculosis in 22 high-burden countries: a mathematical modelling study Dr Peter J Dodd, PhD, Elizabeth Gardiner, MSc, Renia Coghlan,

Worldwide trends in insufficient physical activity from 2001 to 2016: a pooled analysis of 358 population-based surveys with 1·9 million participants

Neonatal infection: a major burden with minimal funding

Burden of obstetric fistula: from measurement to action

Volume 382, Issue 9895, Pages (September 2013)

Effect of HSV-2 infection on subsequent HIV acquisition: an updated systematic review and meta-analysis Katharine J Looker, PhD, Jocelyn A R Elmes, PhD,

National and subnational all-cause and cause-specific child mortality in China, 1996– 2015: a systematic analysis with implications for the Sustainable.

The effect of a transition into poverty on child and maternal mental health: a longitudinal analysis of the UK Millennium Cohort Study Dr Sophie Wickham,

No. 342-Hepatitis B and Pregnancy

National, regional, and global prevalence of smoking during pregnancy in the general population: a systematic review and meta-analysis Shannon Lange,

Prevalence of tuberculosis, hepatitis C virus, and HIV in homeless people: a systematic review and meta-analysis Ulla Beijer, PhD, Achim Wolf, MSc, Dr.

Maternal pre-pregnancy infection with hepatitis B virus and the risk of preterm birth: a population-based cohort study Jue Liu, PhD, Shikun Zhang, MD,

Sundeep Salvi, MD, DNB, PhD, FCCP, Peter J. Barnes, DM, FCCP CHEST

Equity in antenatal care quality: an analysis of 91 national household surveys Catherine Arsenault, PhD, Keely Jordan, MSc, Dennis Lee, BA, Girmaye Dinsa,

Child mortality in England compared with Sweden: a birth cohort study

Effect of increased concentrations of atmospheric carbon dioxide on the global threat of zinc deficiency: a modelling study Dr Samuel S Myers, MD, K.

Volume 18, Issue 12, Pages (December 2017)

Reproduction at an advanced maternal age and maternal health

Changes in chlamydia prevalence and duration of infection estimated from testing and diagnosis rates in England: a model-based analysis using surveillance.

Prevalence of malaria infection in pregnant women compared with children for tracking malaria transmission in sub-Saharan Africa: a systematic review.

Measuring health and economic wellbeing in the Sustainable Development Goals era: development of a poverty-free life expectancy metric and estimates for.

Health consequences of exposure to e-waste: a systematic review

Socioeconomic inequality in neonatal mortality in countries of low and middle income: a multicountry analysis Britt McKinnon, MSc, Sam Harper, PhD, Prof.

Cost-effectiveness of the controlled temperature chain for the hepatitis B virus birth dose vaccine in various global settings: a modelling study Nick.

Risk of poor development in young children in low-income and middle-income countries: an estimation and analysis at the global, regional, and country.

Levels and trends in contraceptive prevalence, unmet need, and demand for family planning for 29 states and union territories in India: a modelling study.

Causes of vision loss worldwide, 1990–2010: a systematic analysis

Post-2015 health goals: could country-specific targets supplement global ones? Robert L Cohen, David M Bishai, Y Natalia Alfonso, Shyama Kuruvilla, Julian.

Emerging cancer trends among young adults in the USA: analysis of a population-based cancer registry Hyuna Sung, PhD, Rebecca L Siegel, MPH, Philip S.

Volume 387, Issue 10017, Pages (January 2016)

Estimated risk of placental infection and low birthweight attributable to Plasmodium falciparum malaria in Africa in 2010: a modelling study Dr Patrick.

Peter J White, P Joanna Lewis The Lancet Public Health

Forecasting the care needs of the older population in England over the next 20 years: estimates from the Population Ageing and Care Simulation (PACSim)

Tobacco use among people living with HIV: analysis of data from Demographic and Health Surveys from 28 low-income and middle-income countries Dr Noreen.

Anna J Dare, Calvin Ke, Wilson Suraweera, Peter Rodriguez, Prabhat Jha

Child mortality in England compared with Sweden: a birth cohort study

Hypoglycemia and the Full-Term Newborn: How Well Does Birth Weight for Gestational Age Predict Risk? Teresa S. Johnson, RN, PhD Journal of Obstetric,

Burden of childhood tuberculosis in 22 high-burden countries: a mathematical modelling study Dr Peter J Dodd, PhD, Elizabeth Gardiner, MSc, Renia Coghlan,

Thank you to our diverse (but not diverse enough) reviewers

Prenatal exposure to sand and dust storms and children's cognitive function in China: a quasi-experimental study Zhihui Li, MS, Lincoln Chen, MD, Mingqiang.

Volume 387, Issue 10017, Pages (January 2016)

Global burden of maternal and congenital syphilis in 2008 and 2012: a health systems modelling study N Saman Wijesooriya, MPH, Roger W Rochat, MD, Mary.

Volume 388, Issue 10049, Pages (September 2016)

Preventive malaria treatment for contacts of patients with Ebola virus disease in the context of the west Africa 2014–15 Ebola virus disease response:

National, regional, and global levels and trends in neonatal mortality between 1990 and 2017, with scenario-based projections to 2030: a systematic analysis

Anaesthesia-related maternal mortality in low-income and middle-income countries: a systematic review and meta-analysis Soha Sobhy, MBBS, Prof Javier.

Age-targeted tuberculosis vaccination in China and implications for vaccine development: a modelling study Rebecca C Harris, PhD, Tom Sumner, PhD, Gwenan.

Reducing the cardiovascular disease burden for people of all ages in the Americas region: analysis of mortality data, 2000–15 Prof Peter Lloyd-Sherlock,

First estimates of the global and regional incidence of neonatal herpes infection Dr Katharine J Looker, PhD, Amalia S Magaret, PhD, Margaret T May, PhD,

Levels and trends in contraceptive prevalence, unmet need, and demand for family planning for 29 states and union territories in India: a modelling study.

Unpacking the null: a post-hoc analysis of a cluster-randomised controlled trial of the WHO Safe Childbirth Checklist in Uttar Pradesh, India (BetterBirth)

Nina Brooks, MPP, Eran Bendavid, MD, Grant Miller, PhD

Presentation transcript:

First estimates of the global and regional incidence of neonatal herpes infection Dr Katharine J Looker, PhD, Amalia S Magaret, PhD, Margaret T May, PhD, Katherine M E Turner, PhD, Peter Vickerman, PhD, Lori M Newman, MD, Sami L Gottlieb, MD The Lancet Global Health Volume 5, Issue 3, Pages e300-e309 (March 2017) DOI: 10.1016/S2214-109X(16)30362-X Copyright © 2017 World Health Organization Terms and Conditions

Figure 1 Equation used to generate annual numbers of incident neonatal infections For this equation, N(a)HSV-s is the annual number of incident neonatal HSV infections corresponding to maternal year of age a due to HSV type s where s=1 or 2; B(a) is the annual number of livebirths at maternal age a;16 F(a)HSV-s is the proportion of women with prevalent HSV-s infection at age a;8,9 rprev_HSV-s is the per-birth risk of neonatal infection from a prevalent maternal HSV-s infection;7 kHSV-s is the maximum proportion of women that can be expected to be infected with HSV-s over a lifetime of exposure;8,9 λHSV-s is the incidence of HSV-s infection per year among (uninfected) women;8,9 xHSV-s is the average number of days between HSV-s infection and the development of protective IgG antibodies (ie, the window for transmission associated with an incident maternal HSV-s infection);19,20 rincid_HSV-s is the per-birth risk of neonatal infection from an incident maternal HSV-s infection that occurs near labour and before antibodies have developed.7,17,18 The Lancet Global Health 2017 5, e300-e309DOI: (10.1016/S2214-109X(16)30362-X) Copyright © 2017 World Health Organization Terms and Conditions

Figure 2 Estimates of the annual number of cases and rate per 100 000 livebirths of neonatal herpes during 2010–15 (B), and relative contribution of HSV-1 versus HSV-2 (A) and prevalent versus incident HSV infection in the mother (C) to the numbers of cases, by WHO region The Lancet Global Health 2017 5, e300-e309DOI: (10.1016/S2214-109X(16)30362-X) Copyright © 2017 World Health Organization Terms and Conditions

Figure 3 Percentage of neonatal herpes cases due to (A) HSV-1 versus HSV-2; and (B) prevalent versus incident maternal HSV infection during 2010–15, by age group of the mother The Lancet Global Health 2017 5, e300-e309DOI: (10.1016/S2214-109X(16)30362-X) Copyright © 2017 World Health Organization Terms and Conditions