Fig. S1 + leu - leu A 5 * 4 3 Serum TSH (ng/ml) 2 1.

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Presentation transcript:

Fig. S1 + leu - leu A 5 * 4 3 Serum TSH (ng/ml) 2 1

* * * * - - Fig. S2 A B + + + leu - leu 4 26 3 24 # Average Body Weight (g) * Average Food Intake (g) 2 * 22 1 20 - + - + TRH Ab TRH Ab

* Fig. S3 A B - leu/ - TRH Ab/ - T3 - leu/ + TRH Ab/ - T3 4 26 * # 25 3 # Average Body Weight (g) 24 Average Food Intake (g) 2 23 1 22 21

* * * * - - Fig. S4 A B + + + leu - leu 4 26 # 3 24 Average Body Weight (g) * Average Food Intake (g) 2 22 1 20 - + - + Ad-shCREB Ad-shCREB

* Fig. S5 A B - leu/ - shCREB/ - TRH - leu/ + shCREB/ - TRH 3.0 30 * # 2.0 20 Average Food Intake (g) Average Body Weight (g) 1.0 10