Volume 84, Issue 3, Pages (September 2013)

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Presentation transcript:

Volume 84, Issue 3, Pages 562-569 (September 2013) Low C4 gene copy numbers are associated with superior graft survival in patients transplanted with a deceased donor kidney Jakob T. Bay, Lone Schejbel, Hans O. Madsen, Søren S. Sørensen, Jesper M. Hansen, Peter Garred Kidney International Volume 84, Issue 3, Pages 562-569 (September 2013) DOI: 10.1038/ki.2013.195 Copyright © 2013 International Society of Nephrology Terms and Conditions

Figure 1 Correlations between serum levels and numbers of C4A, C4B, and total C4 genes in patients and controls. Kidney International 2013 84, 562-569DOI: (10.1038/ki.2013.195) Copyright © 2013 International Society of Nephrology Terms and Conditions

Figure 2 Kaplan–Meier survival curve of kidney graft survival according to C4 genomic copy number (GCN), <4 or ≥4. (a) The 5-year overall kidney graft survival (P=0.010). (b) The 5-year death-censored kidney graft survival (P=0.021). Kidney International 2013 84, 562-569DOI: (10.1038/ki.2013.195) Copyright © 2013 International Society of Nephrology Terms and Conditions

Figure 3 The assays were tested in two different real-time PCR platforms, Stratagene MX3005P and LightCycler LC480. Only the LightCycler had the accuracy necessary to detect variations in copy numbers and was further used. Kidney International 2013 84, 562-569DOI: (10.1038/ki.2013.195) Copyright © 2013 International Society of Nephrology Terms and Conditions