Phylogeographic Differentiation of Mitochondrial DNA in Han Chinese

Slides:



Advertisements
Similar presentations
Nuclear and Mitochondrial DNA Analysis of a 2,000-Year-Old Necropolis in the Egyin Gol Valley of Mongolia Christine Keyser-Tracqui, Eric Crubézy, Bertrand.
Advertisements

Previous Estimates of Mitochondrial DNA Mutation Level Variance Did Not Account for Sampling Error: Comparing the mtDNA Genetic Bottleneck in Mice and.
Connexin Mutations in Skin Disease and Hearing Loss David P. Kelsell, Wei-Li Di, Mark J. Houseman The American Journal of Human Genetics Volume 68, Issue.
Differential Relationship of DNA Replication Timing to Different Forms of Human Mutation and Variation Amnon Koren, Paz Polak, James Nemesh, Jacob J. Michaelson,
Functional Analysis of the Neurofibromatosis Type 2 Protein by Means of Disease- Causing Point Mutations Renee P. Stokowski, David R. Cox The American.
Gene Preference in Maple Syrup Urine Disease Mary M. Nellis, Dean J. Danner The American Journal of Human Genetics Volume 68, Issue 1, Pages (January.
Ethiopian Mitochondrial DNA Heritage: Tracking Gene Flow Across and Around the Gate of Tears Toomas Kivisild, Maere Reidla, Ene Metspalu, Alexandra Rosa,
The Duty to Recontact: Attitudes of Genetics Service Providers Jennifer L. Fitzpatrick, Cecil Hahn, Teresa Costa, Marlene J. Huggins The American Journal.
Peopling of Sahul: mtDNA Variation in Aboriginal Australian and Papua New Guinean Populations Alan J. Redd, Mark Stoneking The American Journal of Human.
Statistical Considerations for Immunohistochemistry Panel Development after Gene Expression Profiling of Human Cancers  Rebecca A. Betensky, Catherine.
Analysis of Mitochondrial DNA Diversity in the Aleuts of the Commander Islands and Its Implications for the Genetic History of Beringia  Olga A. Derbeneva,
MtDNA Diversity in Chukchi and Siberian Eskimos: Implications for the Genetic History of Ancient Beringia and the Peopling of the New World  Yelena B.
A Mitochondrial Stratigraphy for Island Southeast Asia
Phylogeographic Analysis of Mitochondrial DNA in Northern Asian Populations  Miroslava Derenko, Boris Malyarchuk, Tomasz Grzybowski, Galina Denisova, Irina.
Genetic Evidence for the Proto-Austronesian Homeland in Asia: mtDNA and Nuclear DNA Variation in Taiwanese Aboriginal Tribes  Terry Melton, Stephanie.
The Diversity Present in 5140 Human Mitochondrial Genomes
Verónica Fernandes, Farida Alshamali, Marco Alves, Marta D
Mitochondrial Genome Diversity of Native Americans Supports a Single Early Entry of Founder Populations into America  Wilson A. Silva, Jr., Sandro L.
Was ADH1B under Selection in European Populations?
The Ancestry of Brazilian mtDNA Lineages
Miroslava V. Derenko, Tomasz Grzybowski, Boris A
The Structure of Diversity within New World Mitochondrial DNA Haplogroups: Implications for the Prehistory of North America  Ripan S. Malhi, Jason A.
Shaoyu Zhou, Keyaunoosh Kassauei, David J. Cutler, Giulia C
The Archaeogenetics of Europe
P. F. Chinnery, G. A. Taylor, N. Howell, D. T. Brown, T. J. Parsons, D
Do the Four Clades of the mtDNA Haplogroup L2 Evolve at Different Rates?  Antonio Torroni, Chiara Rengo, Valentina Guida, Fulvio Cruciani, Daniele Sellitto,
A Signal, from Human mtDNA, of Postglacial Recolonization in Europe
Genetics, Individuality, and Medicine in the 21st Century*
Xifeng Wu, Jian Gu, H. Barton Grossman, Christopher I
Ethiopian Mitochondrial DNA Heritage: Tracking Gene Flow Across and Around the Gate of Tears  Toomas Kivisild, Maere Reidla, Ene Metspalu, Alexandra Rosa,
MtDNA Haplogroup X: An Ancient Link between Europe/Western Asia and North America?  Michael D. Brown, Seyed H. Hosseini, Antonio Torroni, Hans-Jürgen.
Agnar Helgason, Sigrún Sigurðardóttir, Jeffrey R
The Matrilineal Ancestry of Ashkenazi Jewry: Portrait of a Recent Founder Event  Doron M. Behar, Ene Metspalu, Toomas Kivisild, Alessandro Achilli, Yarin.
The Dual Origin of the Malagasy in Island Southeast Asia and East Africa: Evidence from Maternal and Paternal Lineages  Matthew E. Hurles, Bryan C. Sykes,
Maternal History of Oceania from Complete mtDNA Genomes: Contrasting Ancient Diversity with Recent Homogenization Due to the Austronesian Expansion  Ana T.
In Search of Geographical Patterns in European Mitochondrial DNA
A “Copernican” Reassessment of the Human Mitochondrial DNA Tree from its Root  Doron M. Behar, Mannis van Oven, Saharon Rosset, Mait Metspalu, Eva-Liis.
Volume 19, Issue 1, Pages 1-8 (January 2009)
MtDNA Variation among Greenland Eskimos: The Edge of the Beringian Expansion  Juliette Saillard, Peter Forster, Niels Lynnerup, Hans-Jürgen Bandelt, Søren.
MtDNA Diversity in Chukchi and Siberian Eskimos: Implications for the Genetic History of Ancient Beringia and the Peopling of the New World  Yelena B.
Lluís Quintana-Murci, Raphaëlle Chaix, R. Spencer Wells, Doron M
Mitochondrial Haplogroup U5b3: A Distant Echo of the Epipaleolithic in Italy and the Legacy of the Early Sardinians  Maria Pala, Alessandro Achilli, Anna.
Olga A. Derbeneva, Elena B. Starikovskaya, Douglas C. Wallace, Rem I
Erratum The American Journal of Human Genetics
The Emerging Tree of West Eurasian mtDNAs: A Synthesis of Control-Region Sequences and RFLPs  Vincent Macaulay, Martin Richards, Eileen Hickey, Emilce.
A Revised Root for the Human Y Chromosomal Phylogenetic Tree: The Origin of Patrilineal Diversity in Africa  Fulvio Cruciani, Beniamino Trombetta, Andrea.
Phylogenetic Network for European mtDNA
Lluís Quintana-Murci, Raphaëlle Chaix, R. Spencer Wells, Doron M
Meiotic Microdeletion Breakpoints in the BRCA1 Gene Are Significantly Associated with Symmetric DNA-Sequence Elements  Beatrice Schmucker, Michael Krawczak 
Reduced-Median-Network Analysis of Complete Mitochondrial DNA Coding-Region Sequences for the Major African, Asian, and European Haplogroups  Corinna.
The Genetic Heritage of the Earliest Settlers Persists Both in Indian Tribal and Caste Populations  T. Kivisild, S. Rootsi, M. Metspalu, S. Mastana, K.
Evolutionary History of the ADRB2 Gene in Humans
Saami and Berbers—An Unexpected Mitochondrial DNA Link
mtDNA Affinities of the Peoples of North-Central Mexico
Phylogeny of East Asian Mitochondrial DNA Lineages Inferred from Complete Sequences  Qing-Peng Kong, Yong-Gang Yao, Chang Sun, Hans-Jürgen Bandelt, Chun-Ling.
A Second Recombination Hotspot Associated with SHOX Deletions
Leslie S. Emery, Kevin M. Magnaye, Abigail W. Bigham, Joshua M
A Gene for an Autosomal Dominant Scleroatrophic Syndrome Predisposing to Skin Cancer (Huriez Syndrome) Maps to Chromosome 4q23  Young-Ae Lee, Howard P.
BRCA1 and BRCA2 Testing: Weighing the Demand against the Benefits
The Molecular Dissection of mtDNA Haplogroup H Confirms That the Franco-Cantabrian Glacial Refuge Was a Major Source for the European Gene Pool  Alessandro.
Anne C. Stone, Mark Stoneking  The American Journal of Human Genetics 
Familial Progressive Sensorineural Deafness Is Mainly Due to the mtDNA A1555G Mutation and Is Enhanced by Treatment with Aminoglycosides  Xavier Estivill,
On the Etruscan Mitochondrial DNA Contribution to Modern Humans
MtDNA Variation in the South African Kung and Khwe—and Their Genetic Relationships to Other African Populations  Yu-Sheng Chen, Antonel Olckers, Theodore.
A Highly Unstable Recent Mutation in Human mtDNA
Distribution Patterns of Postmortem Damage in Human Mitochondrial DNA
Saami and Berbers—An Unexpected Mitochondrial DNA Link
Messages through Bottlenecks: On the Combined Use of Slow and Fast Evolving Polymorphic Markers on the Human Y Chromosome  Peter de Knijff  The American.
Hannah R. Elliott, David C. Samuels, James A. Eden, Caroline L
A Chromosomal Deletion Map of Human Malformations
Presentation transcript:

Phylogeographic Differentiation of Mitochondrial DNA in Han Chinese Yong-Gang Yao, Qing-Peng Kong, Hans-Jürgen Bandelt, Toomas Kivisild, Ya-Ping Zhang  The American Journal of Human Genetics  Volume 70, Issue 3, Pages 635-651 (March 2002) DOI: 10.1086/338999 Copyright © 2002 The American Society of Human Genetics Terms and Conditions

Figure 1 Geographic locations of the Han samples under study The American Journal of Human Genetics 2002 70, 635-651DOI: (10.1086/338999) Copyright © 2002 The American Society of Human Genetics Terms and Conditions

Figure 2 Classification tree of the mtDNA haplogroups observed in Han Chinese. The diagnostic mutations considered here (relative to the revised CRS; Andrews et al. 1999) are indicated on the branches. Nucleotide changes are specified for transversions by suffixes, and “d” indicates deletion; mutations recurrent in this tree are underlined. The revised CRS differs from the root of haplogroup R by mutations at 73, 2706, 7028, 11719, and 14766 that are characteristic of HV or H and by seven private mutations at 263, 315+C, 750, 1438, 4769, 8860, and 15326 (Andrews et al. 1999). The American Journal of Human Genetics 2002 70, 635-651DOI: (10.1086/338999) Copyright © 2002 The American Society of Human Genetics Terms and Conditions

Figure 3 PC map of the mtDNA data (with respect to the basal haplogroup profiles) of 13 regional Han samples. The American Journal of Human Genetics 2002 70, 635-651DOI: (10.1086/338999) Copyright © 2002 The American Society of Human Genetics Terms and Conditions

Feedback: Privacy Policy Feedback
Do Not Sell My Personal Information
About project: SlidePlayer Terms of Service

© 2025 SlidePlayer.com. Inc. All rights reserved.