Angel Lanas, Ping Wu, Jennie Medin, Edward J. Mills 

Slides:



Advertisements
Similar presentations
Irritable Bowel Syndrome and Microscopic Colitis: A Systematic Review and Meta- analysis Eline J.C.A. Kamp, John S. Kane, Alexander C. Ford Clinical Gastroenterology.
Advertisements

Risk of Neoplasia After Colectomy in Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-analysis Lauranne A.A.P. Derikx, Loes H.C.
Wai–Kit Lo, Walter W. Chan  Clinical Gastroenterology and Hepatology 
Ursodeoxycholic Acid and Diets Higher in Fat Prevent Gallbladder Stones During Weight Loss: A Meta-analysis of Randomized Controlled Trials  Caroline.
Junya Tsurukiri, Masahito Ueno, Naoyuki Kaneko 
Abnormal Liver Tests and Fatty Liver on Ultrasound
Coffee Reduces Risk for Hepatocellular Carcinoma: An Updated Meta-analysis  Francesca Bravi, Cristina Bosetti, Alessandra Tavani, Silvano Gallus, Carlo.
Evidence for Endoscopic Ulcers as Meaningful Surrogate Endpoint for Clinically Significant Upper Gastrointestinal Harm  Andrew Moore, Ingvar Bjarnason,
Efficacy of Topical 5-Aminosalicylates in Preventing Relapse of Quiescent Ulcerative Colitis: A Meta-analysis  Alexander C. Ford, Khurram J. Khan, William.
A Rare Cause of Life-Threatening Upper Gastrointestinal Bleeding
Pichamol Jirapinyo, Christopher C. Thompson 
Proton Pump Inhibitors for Gastroduodenal Damage Related to Nonsteroidal Anti- inflammatory Drugs or Aspirin: Twelve Important Questions for Clinical Practice 
Ursodeoxycholic Acid and Diets Higher in Fat Prevent Gallbladder Stones During Weight Loss: A Meta-analysis of Randomized Controlled Trials  Caroline.
Shou–Jiang Tang, Feriyl Bhaijee 
Risk of Gastrointestinal Bleeding in Patients Taking Non–Vitamin K Antagonist Oral Anticoagulants: A Systematic Review and Meta-analysis  Corey S. Miller,
Morgagni's Hernia Clinical Gastroenterology and Hepatology
A Shocking Cystory Clinical Gastroenterology and Hepatology
Prevalence of Irritable Bowel Syndrome–type Symptoms in Patients With Celiac Disease: A Meta-analysis  Anita Sainsbury, David S. Sanders, Alexander C.
Prevalence of Dyspepsia in Individuals With Gastroesophageal Reflux–Type Symptoms in the Community: A Systematic Review and Meta-analysis  Leonardo H.
Rebekah S. Wieland, Richard S. Zubarik, Maryam J. Zenali 
Georg Elias, Nabil Toubia  Clinical Gastroenterology and Hepatology 
Todd H. Baron, Patrick S. Kamath, Robert D. McBane 
Metoclopramide Nasal Spray Reduces Symptoms of Gastroparesis in Women, but not Men, With Diabetes: Results of a Phase 2B Randomized Study  Henry P. Parkman,
Chan-Ming Chen, Chao-Chin Chao, Hsin-Hui Chiu 
Tomislav Brkic, Mirjana Kalauz, Hrvoje Ivekovic 
Personalizing Colorectal Cancer Screening: A Systematic Review of Models to Predict Risk of Colorectal Neoplasia  Gene K. Ma, Uri Ladabaum  Clinical Gastroenterology.
Proximal Esophageal Varices: A Rare Yet Treatable Cause of Hemorrhage
Diffuse Large B-Cell Lymphoma of the Small Bowel as an Unusual Cause for Recurrent Obscure Gastrointestinal Bleeding: Diagnosis by Video Capsule Endoscopy 
Activity-Based Costing and Management in a Hospital-Based GI Unit
Bisphosphonates Are Associated With Reduced Risk of Colorectal Cancer: A Systematic Review and Meta-analysis  Siddharth Singh, Abha Goyal Singh, Mohammad.
Endoscopic Therapy for Barrett's Esophagus
AGA Clinical Practice Update on Functional Gastrointestinal Symptoms in Patients With Inflammatory Bowel Disease: Expert Review  Jean-Frederic Colombel,
When Should Screening Stop for Elderly Individuals at Average and Increased Risk for Colorectal Cancer?  Folasade P. May, Samir Gupta  Clinical Gastroenterology.
Emergency Double-Stenting and Surgery for the Successful Management of Massive Upper Gastrointestinal Bleeding Caused by Mycotic Aortic Aneurysm  Gerald.
Tanima Jana, Jorge D. Machicado, Sushovan Guha 
Obstructive Jaundice Caused by Intraductal Hepatocellular Carcinoma
Rapid Disappearance of a Pancreatic Cyst After Steroid Therapy in a Patient With Autoimmune Pancreatitis  Terumi Kamisawa, Hajime Anjiki, Naoto Egawa 
Metastatic Malignant Melanoma of the Gastrointestinal Tract
Abnormal Liver Tests and Fatty Liver on Ultrasound
Effects of Linaclotide in Patients With Irritable Bowel Syndrome With Constipation or Chronic Constipation: A Meta-analysis  Elizabeth J. Videlock, Vivian.
Analysis of Upper Gastrointestinal Adverse Events Among Patients Given Dabigatran in the RE-LY Trial  Peter Bytzer, Stuart J. Connolly, Sean Yang, Michael.
New Models of Gastroenterology Practice
Patient, Procedure, and Endoscopist Risk Factors for Perforation, Bleeding, and Splenic Injury After Colonoscopies  Moussa Laanani, Joël Coste, Pierre-Olivier.
What Is the Prevalence of Clinically Significant Endoscopic Findings in Subjects With Dyspepsia? Systematic Review and Meta-analysis  Alexander C. Ford,
Short-term and Long-term Efficacy of Psychological Therapies for Irritable Bowel Syndrome: A Systematic Review and Meta-analysis  Kelsey T. Laird, Emily.
Peter Bytzer  Clinical Gastroenterology and Hepatology 
Wai–Kit Lo, Walter W. Chan  Clinical Gastroenterology and Hepatology 
Rebecca M. Lovell, Alexander C. Ford 
Mucosal Healing Is Associated With Improved Long-term Outcomes of Patients With Ulcerative Colitis: A Systematic Review and Meta-analysis  Shailja C.
Tamir Ben–Menachem, Jason A. Dominitz 
Junya Tsurukiri, Masahito Ueno, Naoyuki Kaneko 
Gino Caselli, Cecilia Besa, Dahiana Pulgar 
Gender as a Risk Factor for Advanced Neoplasia and Colorectal Cancer: A Systematic Review and Meta-analysis  Stephen P. Nguyen, Stephen Bent, Yea-Hung.
James Allison, Lisa J. Herrinton, Liyan Liu, Jenny Yu, James Lowder 
Hepatic Cyst? Clinical Gastroenterology and Hepatology
Lauren B. Gerson, Melissa A. Batenic, Sharese L
Failure to Renew Prescriptions for Gastroprotective Agents to Patients on Continuous Nonsteroidal Anti-inflammatory Drugs Increases Rate of Upper Gastrointestinal.
Coagulation in Liver Disease: A Guide for the Clinician
Lucía Cea Soriano, Angel Lanas, Montse Soriano-Gabarró, Luis A
Coloduodenal Fistula in Crohn’s Disease
GI Bleeding, Colon Varicosities, and Visceral Enlargement as a Manifestation of Klippel– Trenaunay Syndrome  Fnu Deepinder  Clinical Gastroenterology and.
Electronic Clinical Challenges and Images in GI
Rintaro Hashimoto, Akimichi Chonan 
Adverse Outcomes: Why Bad Things Happen to Good People
Medical Therapy for Refractory Pediatric Crohn’s Disease
M. Babitha Reddy, David M. Poppers, Cora Uram–Tuculescu 
Rintaro Hashimoto, Akimichi Chonan 
Metastatic Malignant Melanoma of the Gastrointestinal Tract
Ursodeoxycholic Acid and Diets Higher in Fat Prevent Gallbladder Stones During Weight Loss: A Meta-analysis of Randomized Controlled Trials  Caroline.
Karanprit Singh, Prateek Chapalamadugu, Peter Malet 
Presentation transcript:

Low Doses of Acetylsalicylic Acid Increase Risk of Gastrointestinal Bleeding in a Meta- Analysis  Angel Lanas, Ping Wu, Jennie Medin, Edward J. Mills  Clinical Gastroenterology and Hepatology  Volume 9, Issue 9, Pages 762-768.e6 (September 2011) DOI: 10.1016/j.cgh.2011.05.020 Copyright © 2011 AGA Institute Terms and Conditions

Figure 1 Bleeding events associated with low-dose ASA alone vs controls. Clinical Gastroenterology and Hepatology 2011 9, 762-768.e6DOI: (10.1016/j.cgh.2011.05.020) Copyright © 2011 AGA Institute Terms and Conditions

Figure 2 Major GI bleeds with low-dose ASA alone vs controls. Clinical Gastroenterology and Hepatology 2011 9, 762-768.e6DOI: (10.1016/j.cgh.2011.05.020) Copyright © 2011 AGA Institute Terms and Conditions

Figure 3 Any bleeding events with clopidogrel plus low-dose ASA and PPI plus low-dose ASA vs low-dose ASA. Clinical Gastroenterology and Hepatology 2011 9, 762-768.e6DOI: (10.1016/j.cgh.2011.05.020) Copyright © 2011 AGA Institute Terms and Conditions

Figure 4 Major GI bleeds with warfarin plus low-dose ASA vs low-dose ASA. Clinical Gastroenterology and Hepatology 2011 9, 762-768.e6DOI: (10.1016/j.cgh.2011.05.020) Copyright © 2011 AGA Institute Terms and Conditions

Supplementary Figure 1 Flow diagram of included studies. (A) Low-dose ASA alone, (B) low-dose ASA plus clopidogrel, (C) low-dose ASA plus anticoagulant therapy, and (D) low-dose ASA plus PPI. Clinical Gastroenterology and Hepatology 2011 9, 762-768.e6DOI: (10.1016/j.cgh.2011.05.020) Copyright © 2011 AGA Institute Terms and Conditions