SBÜ KAYSERİ ERH Doç. Dr. Gökhan Açmaz RETROSPECTIVE EVALUATION OF COLD KNİFE CONE AND LEEP OPERATIONS IN OUR CLINIC SBÜ KAYSERİ ERH Doç. Dr. Gökhan Açmaz

Introduction Cervical cancer is the 4th most common cause of cancer-related deaths in women 470,000 new cases are recognized each year, and over 230,000 women are estimated to have lost their lives. Cold conization and loop electrosurgical excision procedure (LEEP) are two methods used to treat high grade cervical intraepithelial neoplasms (CIN2 and CIN3)

Introduction The aim of this study is to evaluate the complications of cold conization and LEEP methods those performed in our clinic.

Method This retrospective study was performed in the Kayseri Education and Research Hospital of Medicine, Obstetrics and Gynecology Department between 2015-2017 Demographic data of patients with cold conization and LEEP and intraoperative and postoperative complications were compared.

Table 1. Comparison of LEEP and conization procedures intraoperatively and postoperatively. LEEP (n=120) Conization(n=118) p - Value Age 42,92 42,58 0,675 HPV positivity 85/120 82/118 0,822 Endocervical gland involvement 12/120 18/118 0,225 Surgical border positivity 10/120 13/118 0,486 Hysterectomy 2/120 3/118 0,640 Major bleeding 1/120 2/118 0,983 Major infections 0/120 0/118 NA Organ damage PID 0,987 Minor bleeding 27/120 35/118 0,027

Conclusion LEEP and cold conization can be easily applied in the treatment of high-grade cervical precancerous lesions These methods provide both diagnosis and treatment. As a major complication, there is no difference between two groups Both methods seem to be an alternative to each other in the treatment of high grade cervical precancerous lesions.