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Nat. Rev. Cardiol. doi:10.1038/nrcardio.2017.1 Figure 1 3D transoesophageal echocardiography for the characterization of primary mitral regurgitation Figure 1 | 3D transoesophageal echocardiography for the characterization of primary mitral regurgitation. a | An example of Barlow mitral valve disease with redundant tissue affecting the entire posterior mitral leaflet (PML) and the central and posterior scallops of the anterior mitral leaflet (AML) causing prolapse of both leaflets. b | An example of fibroelastic deficiency with isolated involvement of the central scallop of the posterior mitral leaflet (P2) and chorda rupture (asterisk). AoV, aortic valve; LAA, left atrial appendage. Bax, J. J. & Delgado, V. (2017) Advanced imaging in valvular heart disease Nat. Rev. Cardiol. doi:10.1038/nrcardio.2017.1