Value of Autoantibody Analysis in the Differential Diagnosis of Chronic Cholestatic Liver Disease Piotr Milkiewicz, Hayman Buwaneswaran, Catalina Coltescu,

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Presentation transcript:

Value of Autoantibody Analysis in the Differential Diagnosis of Chronic Cholestatic Liver Disease Piotr Milkiewicz, Hayman Buwaneswaran, Catalina Coltescu, Zakera Shums, Gary L. Norman, E. Jenny Heathcote Clinical Gastroenterology and Hepatology Volume 7, Issue 12, Pages 1355-1360 (December 2009) DOI: 10.1016/j.cgh.2009.07.012 Copyright © 2009 AGA Institute Terms and Conditions

Figure 1 Autoantibodies in complete PBC cohort. Cutoff A (20 units) for CENP (anti-centromere antibodies) and chromatin ELISA; cutoff B (25 units) for all other ELISAs. Clinical Gastroenterology and Hepatology 2009 7, 1355-1360DOI: (10.1016/j.cgh.2009.07.012) Copyright © 2009 AGA Institute Terms and Conditions

Figure 2 Overlap of specificities in patients with PBC. Clinical Gastroenterology and Hepatology 2009 7, 1355-1360DOI: (10.1016/j.cgh.2009.07.012) Copyright © 2009 AGA Institute Terms and Conditions

Figure 3 Overlap of specificities in patients with AMA-negative PBC. Clinical Gastroenterology and Hepatology 2009 7, 1355-1360DOI: (10.1016/j.cgh.2009.07.012) Copyright © 2009 AGA Institute Terms and Conditions

Figure 4 Overlap of specificities in patients with AMA-negative PBC. Clinical Gastroenterology and Hepatology 2009 7, 1355-1360DOI: (10.1016/j.cgh.2009.07.012) Copyright © 2009 AGA Institute Terms and Conditions