Dose-dependent response to intramuscular botulinum toxin type A for upper-limb spasticity in patients after a stroke 1  Martin K Childers, DO, PhD, Allison Brashear, MD, Patricia Jozefczyk, MD, Michael Reding, MD, David Alexander, MD, David Good, MD, Jennifer M Walcott, MS, S.W Jenkins, MD, Catherine Turkel, PharmD, Patricia T Molloy, MD  Archives of Physical Medicine and Rehabilitation  Volume 85, Issue 7, Pages 1063-1069 (July 2004) DOI: 10.1016/j.apmr.2003.10.015

Fig 1 Participant flow, interventions, and efficacy measurements. ∗Efficacy measures after the first treatment cycle included: MAS scores (wrist, elbow, fingers), physician and patient global assessments, pain assessment, FIM, and SF-36. †Efficacy measures after the second treatment cycle included: MAS scores (wrist) and global assessments. Archives of Physical Medicine and Rehabilitation 2004 85, 1063-1069DOI: (10.1016/j.apmr.2003.10.015)

Fig 2 Change in MAS scores at the wrist in subjects with excessive muscle tone after a stroke. NOTE. Data are mean values. Negative scores are clinically desirable. Archives of Physical Medicine and Rehabilitation 2004 85, 1063-1069DOI: (10.1016/j.apmr.2003.10.015)

Fig 3 Change in MAS scores at the elbow in subjects with excessive muscle tone after a stroke. NOTE. Data are mean values. Negative scores are clinically desirable. Archives of Physical Medicine and Rehabilitation 2004 85, 1063-1069DOI: (10.1016/j.apmr.2003.10.015)