Preoperative blood glucose concentrations and postoperative outcomes after elective non-cardiac surgery: an observational study† B.B. Abdelmalak, J.

Slides:

Advertisements

Similar presentations

Reducing the risk of fatal and disabling hypoglycaemia: a comparison of arterial blood sampling systems K.A. Brennan, G. Eapen, D. Turnbull British.

Advertisements

Benefits and risks of epidural analgesia in cardiac surgery†

I. Garutti, L. Puente-Maestu, J. Laso, R. Sevilla, A. Ferrando, I

Incidence and risk factors for intensive care unit admission after bariatric surgery: a multicentre population-based cohort study D.J.R. Morgan, K.M.

Characteristics of pain in hospitalized medical patients, surgical patients, and outpatients attending a pain management centre M.P. Rockett, G. Simpson,

Effect of adductor canal block on pain in patients with severe pain after total knee arthroplasty: a randomized study with individual patient analysis

Tracheal intubation by trainees does not alter the incidence or duration of postoperative sore throat and hoarseness: a teaching hospital-based propensity.

D. M. Baron, H. Hochrieser, M. Posch, B. Metnitz, A. Rhodes, R. P

Efficacy of intraoperative dexmedetomidine infusion on emergence agitation and quality of recovery after nasal surgery S.Y. Kim, J.M. Kim, J.H. Lee,

Changes in sevoflurane plasma concentration with delivery through the oxygenator during on-pump cardiac surgery R. Nitzschke, J. Wilgusch, J.F. Kersten,

Monitoring depth of anaesthesia in a randomized trial decreases the rate of postoperative delirium but not postoperative cognitive dysfunction F.M. Radtke,

A. Kurz, T. Kopyeva, I. Suliman, A. Podolyak, J. You, B. Lewis, C

Preoperative abnormalities in serum sodium concentrations are associated with higher in-hospital mortality in patients undergoing major surgery M. Cecconi,

Differential effects of serum from patients administered distinct anaesthetic techniques on apoptosis in breast cancer cells in vitro: a pilot study

Comparison of coagulation and blood loss during anaesthesia with inhaled isoflurane or intravenous propofol N.L. Law, K.F.J. Ng, M.G. Irwin, J.S.F. Man

Changes in glomerular filtration rate after cardiac surgery with cardiopulmonary bypass in patients with mild preoperative renal dysfunction B.G. Loef,

Dexamethasone alone vs in combination with transcutaneous electrical acupoint stimulation or tropisetron for prevention of postoperative nausea and vomiting.

Perioperative statin therapy in patients at high risk for cardiovascular morbidity undergoing surgery: a review B.A. de Waal, M.P. Buise, A.A.J. van.

Preoperative estimated glomerular filtration rate and the risk of major adverse cardiovascular and cerebrovascular events in non-cardiac surgery‡ A.

Pre-hospital tracheal intubation in patients with traumatic brain injury: systematic review of current evidence E. von Elm, P. Schoettker, I. Henzi,

J.-Y. Hwang, H.-S. Na, Y.-T. Jeon, Y.-J. Ro, C.-S. Kim, S.-H. Do

Role of N-terminal pro B-type natriuretic peptide in identifying patients at high risk for adverse outcome after emergent non-cardiac surgery S. Farzi,

Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries British Journal of Anaesthesia

Inflating LMA with normal saline: 14 yr after

Preoperative supplementation with fibrinogen concentrate in cardiac surgery: A randomized controlled study A. Jeppsson, K. Waldén, C. Roman-Emanuel,

Pain after orthopaedic surgery: differences in patient reported outcomes in the United States vs internationally. An observational study from the PAIN.

Raised serum cardiac troponin I concentrations predict hospital mortality in intensive care unit patients† T. Reynolds, M. Cecconi, P. Collinson, A.

Preadmission statin use improves the outcome of less severe sepsis patients - a population-based propensity score matched cohort study M.G. Lee, C.-C.

Blood glucose concentration profile after 10 mg dexamethasone in non-diabetic and type 2 diabetic patients undergoing abdominal surgery Hans P , Vanthuyne.

Perioperative increase in global blood flow to explicit defined goals and outcomes after surgery: a Cochrane Systematic Review† M.P.W. Grocott, A Dushianthan,

Preoperative levosimendan infusion in combined aortic valve and coronary bypass surgery H Leppikangas, K Järvelä, T Sisto, P Maaranen, M Virtanen, P.

Effect of length of stay in intensive care unit on hospital and long-term mortality of critically ill adult patients T.A. Williams, K.M. Ho, G.J. Dobb,

Impact of preoperative serum creatinine on short- and long-term mortality after cardiac surgery: a cohort study M.H. Bernardi, D. Schmidlin, A. Schiferer,

Age- and therapy-related effects on morphine requirements and plasma concentrations of morphine and its metabolites in postoperative infants N.J. Bouwmeester,

Comparison of the effects of albumin 5%, hydroxyethyl starch 130/0

G.R. Lorello, D.A. Cook, R.L. Johnson, R. Brydges

Perioperative administration of fibrinogen does not increase adverse cardiac and thromboembolic events after cardiac surgery J. Fassl, G. Lurati Buse,

D. Fletcher, V. Martinez British Journal of Anaesthesia

Preoperative evaluation of patients with, or at risk of, coronary artery disease undergoing non-cardiac surgery P.-G. Chassot, A. Delabays, D.R. Spahn

Troponin elevations after non-cardiac, non-vascular surgery are predictive of major adverse cardiac events and mortality: a systematic review and meta-analysis

B. B. Abdelmalak, A Bonilla, E. J. Mascha, A Maheshwari, W. H

Do old pharmacokinetic parameter estimates predict new data?

Is age a predictor of mortality in a UK medical high dependency unit?

Falls and major orthopaedic surgery with peripheral nerve blockade: a systematic review and meta-analysis R.L. Johnson, S.L. Kopp, J.R. Hebl, P.J. Erwin,

Glucose, insulin and potassium applied as perioperative hyperinsulinaemic normoglycaemic clamp: effects on inflammatory response during coronary artery.

Moderate dosage of tranexamic acid during cardiac surgery with cardiopulmonary bypass and convulsive seizures: incidence and clinical outcome A. Koster,

II. Should anaesthetists stop infusing isotonic saline?

Validation of a measurement tool for self-assessment of teamwork in intensive care J Weller, B Shulruf, J Torrie, R Frengley, M Boyd, A Paul, B Yee, P.

C. J. Payne, S. C. Gibson, G. Bryce, A. G. Jardine, C. Berry, D. B

Intraoperative tissue oxygenation and postoperative outcomes after major non-cardiac surgery: an observational study† B.B. Abdelmalak, J.P. Cata, A.

Influence of increased left ventricular myocardial mass on early and late mortality after cardiac surgery M.M. Weiner, D.L. Reich, H.M. Lin, M. Krol,

Increase in endogenous erythropoietin synthesis through the normobaric oxygen paradox in cardiac surgery patients Y. Ciccarella, C. Balestra, J. Valsamis,

J Lee, S Gupta, C Price, A.P. Baranowski

Chronic widespread pain, including fibromyalgia: a pathway for care developed by the British Pain Society J. Lee, B. Ellis, C. Price, A.P. Baranowski

Multivariate model for predicting postoperative blood loss in children undergoing cardiac surgery: a preliminary study V. Savan, A. Willems, D. Faraoni,

Are perioperative therapeutic doses of statins associated with postoperative pain and opioid consumption after hip surgery under spinal anaesthesia?

Comparison of ropivacaine 0. 5% (in glucose 5%) with bupivacaine 0

Influence of preoperative cognitive status on propofol requirement to maintain hypnosis in the elderly F.-Z. Laalou, M Egard, M Guillot, E Noll, G Taglang,

Association between preoperative statin therapy and postoperative change in glomerular filtration rate in endovascular aortic surgery M.Y. Argalious,

Systematic review of the QoR-15 score, a patient- reported outcome measure measuring quality of recovery after surgery and anaesthesia J. Kleif, J. Waage,

High-sensitive cardiac troponin T measurements in prediction of non-cardiac complications after major abdominal surgery† P.G. Noordzij, O. van Geffen,

Regional anaesthesia to improve pain outcomes in paediatric surgical patients: a qualitative systematic review of randomized controlled trials S. Suresh,

Assessment of preoperative fluid depletion using bioimpedance analysis

Levosimendan pre-treatment improves outcomes in patients undergoing coronary artery bypass graft surgery† L. Tritapepe, V. De Santis, D. Vitale, F. Guarracino,

Association between day and time of admission to critical care and acute hospital outcome for unplanned admissions to adult general critical care units:

Nottingham Hip Fracture Score as a predictor of one year mortality in patients undergoing surgical repair of fractured neck of femur M.D. Wiles, C.G.

H.D. Aya, M. Cecconi, M. Hamilton, A. Rhodes

Effect of concentration of local anaesthetic solution on the ED50 of bupivacaine for supraclavicular brachial plexus block† P.K. Gupta, P.M. Hopkins

Anaesthetic drugs and survival: a Bayesian network meta-analysis of randomized trials in cardiac surgery G. Landoni, T. Greco, G. Biondi-Zoccai, C. Nigro.

R. Parke, S. McGuinness, R. Dixon, A. Jull

Presentation transcript:

Preoperative blood glucose concentrations and postoperative outcomes after elective non-cardiac surgery: an observational study† B.B. Abdelmalak, J. Knittel, J.B. Abdelmalak, J.E. Dalton, E. Christiansen, J. Foss, M. Argalious, R. Zimmerman, G. Van den Berghe British Journal of Anaesthesia Volume 112, Issue 1, Pages 79-88 (January 2014) DOI: 10.1093/bja/aet297 Copyright © 2014 The Author(s) Terms and Conditions

Fig 1 Study flow chart. British Journal of Anaesthesia 2014 112, 79-88DOI: (10.1093/bja/aet297) Copyright © 2014 The Author(s) Terms and Conditions

Fig 2 (a–d) Crude and covariable-adjusted incidence of composite in-hospital morbidity/mortality and 1 yr all-cause mortality for all patients. Estimates given as pointwise 95% confidence bands (confidence bands adjusted for simultaneous comparisons using the Bonferroni method). P-values from the Wald tests assessing the relationship between baseline glucose and each outcome (statistical significance after the Bonferroni correction for simultaneous inference on two outcomes given by asterisks). Covariable-adjusted estimates are adjusted for all factors given in Table 1. To convert to mg dl−1, multiply the mmol litre−1 value by 18. British Journal of Anaesthesia 2014 112, 79-88DOI: (10.1093/bja/aet297) Copyright © 2014 The Author(s) Terms and Conditions

Fig 3 (a–d) Crude and covariable-adjusted incidence of composite in-hospital morbidity/mortality and 1 yr all-cause mortality, by baseline diabetic status. Estimates given as pointwise 95% confidence bands (confidence bands adjusted for simultaneous comparisons using the Bonferroni method). P-values from the Wald tests of equal relationships between baseline glucose and the respective outcome among the patients with and without diagnosed diabetes (statistical significance after the Bonferroni correction for simultaneous inference on two outcomes given by asterisks). Covariable-adjusted estimates are adjusted for all factors given in Table 1. To convert to mg dl−1, multiply the mmol litre−1 value by 18. British Journal of Anaesthesia 2014 112, 79-88DOI: (10.1093/bja/aet297) Copyright © 2014 The Author(s) Terms and Conditions

Fig 4 Covariable-adjusted OR for composite in-hospital morbidity/mortality and 1 yr mortality as a function of preoperative serum glucose concentration. Shaded regions represent pointwise 95% CIs, adjusted for simultaneous inference on two outcomes. ORs represent patients with diabetes diagnosis (DM) vs those without diabetes diagnosis (Non-DM). Estimates are adjusted for all factors given in Table 1. To convert to mg dl−1, multiply the mmol litre−1 value by 18. British Journal of Anaesthesia 2014 112, 79-88DOI: (10.1093/bja/aet297) Copyright © 2014 The Author(s) Terms and Conditions