Cyclosporine in the Treatment of Dermatologic Disease: An Update

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Presentation transcript:

Cyclosporine in the Treatment of Dermatologic Disease: An Update Katherine K. Lim, M.D., W.P. Daniel Su, M.D., Arnold L. Schroeter, M.D., Candace J. Sabers, Ph.D., Robert T. Abraham, Ph.D., Mark R. Pittelkow, M.D.  Mayo Clinic Proceedings  Volume 71, Issue 12, Pages 1182-1191 (December 1996) DOI: 10.4065/71.12.1182 Copyright © 1996 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 1 T-cell activation and points of inhibition by established and newly discovered immunosuppressants. Ag = antigen; APC = antigen processing cell; CsA = cyclosporine (cyclosporin A); G0-G2 = M, S, phases of cell cycle; IL = interleukin; MHC = major histocompatibility complex; TCR = T-cell antigen receptor. Mayo Clinic Proceedings 1996 71, 1182-1191DOI: (10.4065/71.12.1182) Copyright © 1996 Mayo Foundation for Medical Education and Research Terms and Conditions