Carolyn Y. Ho et al. JCHF 2015;3:

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Carolyn Y. Ho et al. JCHF 2015;3:180-188 Changes in LVEDD z-Scores Over Time in Study Participants (A) Changes during treatment with diltiazem or placebo in the full cohort. The 2 treatment groups diverged over time (interaction between time and treatment, p = 0.003), with significant pairwise differences 12 (p = 0.01) and 24 (p < 0.001) months. (B) Changes during the year after the end of treatment with diltiazem or placebo in the 29 subjects with available follow-up. The 2 treatment groups again diverged over time (interaction between time and treatment, p = 0.047), with a significant pairwise difference at the end of treatment (p = 0.005). The pairwise difference 1 year after discontinuation of diltiazem was attenuated but remained significant (p = 0.02). Error bars are standard errors. LVEDD = left ventricular end-diastolic diameter. Carolyn Y. Ho et al. JCHF 2015;3:180-188 American College of Cardiology Foundation