Trastuzumab-Induced Cardiotoxicity: Heart Failure at the Crossroads

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Presentation transcript:

Trastuzumab-Induced Cardiotoxicity: Heart Failure at the Crossroads Partho P. Sengupta, MD, Donald W. Northfelt, MD, Federico Gentile, MD, Jose L. Zamorano, MD, Bijoy K. Khandheria, MD Mayo Clinic Proceedings Volume 83, Issue 2, Pages 197-203 (February 2008) DOI: 10.4065/83.2.197 Copyright © 2008 Mayo Foundation for Medical Education and Research Terms and Conditions

FIGURE Proposed algorithm for monitoring trastuzumab-induced cardiotoxicity. Serial transthoracic echocardiography (ECG) is the preferred technique for assessment of ejection fraction (EF) and diastolic function. Radionuclide ventriculography can be used for determining EF if transthoracic echocardiograms are suboptimal. LV = left ventricular. Mayo Clinic Proceedings 2008 83, 197-203DOI: (10.4065/83.2.197) Copyright © 2008 Mayo Foundation for Medical Education and Research Terms and Conditions