ERCC2/XPD Lys751Gln and Asp312Asn Gene Polymorphism and Lung Cancer Risk: A Meta-Analysis Involving 22 Case–Control Studies Ping Zhan, MD, Qin Wang,

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ERCC2/XPD Lys751Gln and Asp312Asn Gene Polymorphism and Lung Cancer Risk: A Meta-Analysis Involving 22 Case–Control Studies Ping Zhan, MD, Qin Wang, MD, Shu-Zhen Wei, MD, Jing Wang, MD, Qian Qian, MD, Li-Ke Yu, MD, Yong Song, MD, PhD Journal of Thoracic Oncology Volume 5, Issue 9, Pages 1337-1345 (September 2010) DOI: 10.1097/JTO.0b013e3181e7fe2a Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 Forest plot (random-effects model) of lung cancer risk associated with XPD Lys751Gln genotype for CC versus AA. Each box represents the odds ratio (OR) point estimate, and its area is proportional to the weight of the study. The diamond (and broken line) represents the overall summary estimate, with confidence interval (CI) represented by its width. The unbroken vertical line is set at the null value (OR = 1.0). Journal of Thoracic Oncology 2010 5, 1337-1345DOI: (10.1097/JTO.0b013e3181e7fe2a) Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 2 Forest plot (random-effects model) of lung cancer risk associated with XPD Asp312Asn genotype for AA versus GG. Journal of Thoracic Oncology 2010 5, 1337-1345DOI: (10.1097/JTO.0b013e3181e7fe2a) Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 3 Begg's funnel plot of XPD Lys751Gln gene polymorphism and lung cancer risk for CC versus AA. Journal of Thoracic Oncology 2010 5, 1337-1345DOI: (10.1097/JTO.0b013e3181e7fe2a) Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 4 Begg's funnel plot of XPD Asp312Asn gene polymorphism and lung cancer risk for AA versus GG. Journal of Thoracic Oncology 2010 5, 1337-1345DOI: (10.1097/JTO.0b013e3181e7fe2a) Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions