Cellular blue nevi of the eyelid: A possible diagnostic pitfall

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Presentation transcript:

Cellular blue nevi of the eyelid: A possible diagnostic pitfall Qing Wang, Victor Prieto, MD, PhD, Bita Esmaeli, MD, Timothy Kolda, MD, Alexander Lazar, MD, PhD, Doina Ivan, MD, A. Hafeez Diwan, MD, PhD Journal of the American Academy of Dermatology Volume 58, Issue 2, Pages 257-260 (February 2008) DOI: 10.1016/j.jaad.2007.11.014 Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 A, Slit lamp photograph of eyelid, palpebral and bulbar conjunctiva in patient 1 shows well-circumscribed multiple areas of pigmentation involving eyelid and palpebral conjunctiva, bulbar conjunctiva, and orbital fat. B, Surgical specimen with diagram orienting tissue. Journal of the American Academy of Dermatology 2008 58, 257-260DOI: (10.1016/j.jaad.2007.11.014) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 Case 1. A, Cellular blue nevus lower eyelid, 2004; B, uniform HMB45 labeling; C, lack of Mib-1 labeling (for Ki-67); D, 1993 specimen, showing melanoma with obvious atypia, mitoses, and dissimilarity with subsequent lesions. (Original magnifications: A, B, and C, ×100; D, ×200.) Journal of the American Academy of Dermatology 2008 58, 257-260DOI: (10.1016/j.jaad.2007.11.014) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

Fig 3 Case 2. A and B, Combined nevus with intradermal and cellular blue nevus (CBN) components; C, uniform HMB45 labeling of cellular blue component in contrast with nevus; D, lack of Mib-1 labeling (for Ki-67) of CBN component. (Original magnifications: A, C, and D, ×100; B, ×200.) Journal of the American Academy of Dermatology 2008 58, 257-260DOI: (10.1016/j.jaad.2007.11.014) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions