Guillaume Richard-Carpentier, Guy Sauvageau Cell Stem Cell

Slides:

Advertisements

Similar presentations

Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.

Advertisements

What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell

Bone Marrow-Derived Cell Therapy Stimulates Endogenous Cardiomyocyte Progenitors and Promotes Cardiac Repair Francesco S. Loffredo, Matthew L. Steinhauser,

Distribution of Human Embryonic Stem Cell Lines: Who, When, and Where Jennifer B. McCormick, Jason Owen-Smith, Christopher Thomas Scott Cell Stem Cell.

Evolution of the Cancer Stem Cell Model Antonija Kreso, John E. Dick Cell Stem Cell Volume 14, Issue 3, Pages (March 2014) DOI: /j.stem

Nuclear Receptors, RXR, and the Big Bang Ronald M. Evans, David J. Mangelsdorf Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell

Module Map of Stem Cell Genes Guides Creation of Epithelial Cancer Stem Cells David J. Wong, Helen Liu, Todd W. Ridky, David Cassarino, Eran Segal, Howard.

IPSC Crowdsourcing: A Model for Obtaining Large Panels of Stem Cell Lines for Screening Mahendra Rao Cell Stem Cell Volume 13, Issue 4, Pages (October.

Fate Restriction and Multipotency in Retinal Stem Cells Lázaro Centanin, Burkhard Hoeckendorf, Joachim Wittbrodt Cell Stem Cell Volume 9, Issue 6, Pages.

The Mitochondrial Basis of Aging Nuo Sun, Richard J. Youle, Toren Finkel Molecular Cell Volume 61, Issue 5, Pages (March 2016) DOI: /j.molcel

Quiescent Hematopoietic Stem Cells Accumulate DNA Damage during Aging that Is Repaired upon Entry into Cell Cycle Isabel Beerman, Jun Seita, Matthew A.

Myc Represses Primitive Endoderm Differentiation in Pluripotent Stem Cells Keriayn N. Smith, Amar M. Singh, Stephen Dalton Cell Stem Cell Volume 7, Issue.

Reading the Book of Memory: Sparse Sampling versus Dense Mapping of Connectomes H. Sebastian Seung Neuron Volume 62, Issue 1, Pages (April 2009)

Normal and Leukemic Stem Cell Niches: Insights and Therapeutic Opportunities Koen Schepers, Timothy B. Campbell, Emmanuelle Passegué Cell Stem Cell Volume.

Gastrulation Movements: the Logic and the Nuts and Bolts Maria Leptin Developmental Cell Volume 8, Issue 3, Pages (March 2005) DOI: /j.devcel

Quantitative Single-Cell Approaches to Stem Cell Research Martin Etzrodt, Max Endele, Timm Schroeder Cell Stem Cell Volume 15, Issue 5, Pages (November.

Kevin G. Chen, Barbara S. Mallon, Ronald D.G. McKay, Pamela G. Robey

Cutaneous Cancer Stem Cells: β-Catenin Strikes Again

Stress Can Be a Good Thing for Blood Formation

Cancer: Inappropriate Expression of Stem Cell Programs?

Kevin G. Chen, Barbara S. Mallon, Ronald D.G. McKay, Pamela G. Robey

Scott N. Freeman, Kathryn A. Burke, Menfo A. Imoisili, Timothy R. Coté

Leigh Turner, Paul Knoepfler Cell Stem Cell

Men's Health Primary Care: Clinics in Office Practice

Volume 1, Issue 1, Pages (June 2007)

Human Induced Pluripotent Stem Cells: Now Open to Discovery

Grounded: Transcriptional Pausing in Naive mESCs

A Path to Insulin Independence: “The End of the Beginning”

Volume 9, Issue 2, Pages (August 2011)

Gerry P. Crossan, Juan I. Garaycoechea, Ketan J. Patel Cell Stem Cell

Noncoding RNA Landmarks of Pluripotency and Reprogramming

Resistance in the Ribosome: RUNX1, pre-LSCs, and HSPCs

New Japanese Initiatives on Stem Cell Therapies

Volume 2, Issue 6, Pages (June 2008)

MSCs, Macrophages, and Cancer: A Dangerous Ménage-à-Trois

Natalia J. Martinez, Richard I. Gregory Cell Stem Cell

Transplantable Liver Organoids Made from Only Three Ingredients

Regulating Cancer Stem Cells the miR Way

Wing Y. Chang, William L. Stanford Cell Stem Cell

Stem Cell Therapies in Clinical Trials: Progress and Challenges

Wenlian Qiao, Peter W. Zandstra Cell Stem Cell

Human Induced Pluripotent Stem Cells: Now Open to Discovery

Cutaneous Cancer Stem Cells: β-Catenin Strikes Again

TRRAP and the Maintenance of Stemness in Gliomas

MicroRNA Regulation of Stem Cell Fate

AMPK Keeps Tumor Cells from Starving to Death

Resistance in the Ribosome: RUNX1, pre-LSCs, and HSPCs

Utf1: Goldilocks for ESC Bivalency

Putting Two Heads Together to Build a Better Brain

Loukia Yiangou, Alexander D.B. Ross, Kim Jee Goh, Ludovic Vallier

Puma: Mauling the Intestinal Crypt

Targeting β-catenin in CML: Leukemia Stem Cells Beware!

Laura MacPherson, Mark A. Dawson Cell Stem Cell

Transplantable Liver Organoids Made from Only Three Ingredients

A New Therapeutic Target for Leukemia Comes to the Surface

Modifying Mitochondrial tRNAs: Delivering What the Cell Needs

The Promise and Perils of Stem Cell Therapeutics

Cycling toward Elimination of Leukemic Stem Cells

Meddling with METTLs in Normal and Leukemia Stem Cells

Powering Reprogramming with Vitamin C

NO Signals from the Cancer Stem Cell Niche

The Cell Biology of Genomes: Bringing the Double Helix to Life

Selfish Stem Cells Compete with Each Other

Laura MacPherson, Mark A. Dawson Cell Stem Cell

To Infinium, and Beyond! Cancer Cell

ADARs Edit MicroRNAs to Promote Leukemic Stem Cell Activity

Chapter 29 - Stem Cells and Generation of New Cells in the

Mesp1 at the Heart of Mesoderm Lineage Specification

Ye-Guang Chen, Zhongwei Li, Xiao-Fan Wang Cell Stem Cell

Devyn M. Smith, Emily J. Culme-Seymour, Chris Mason Cell Stem Cell

Presentation transcript:

Bringing a Leukemic Stem Cell Gene Signature into Clinics: Are We There Yet? Guillaume Richard-Carpentier, Guy Sauvageau Cell Stem Cell Volume 20, Issue 3, Pages 300-301 (March 2017) DOI: 10.1016/j.stem.2017.02.010 Copyright © 2017 Elsevier Inc. Terms and Conditions

Figure 1 Gene Expression Correlation of GPR56 with Other Genes of the LSC17 Score in the Leucegene Cohort Pearson correlations are performed using log10 RPKM values of 415 primary AML samples from the Leucegene cohort. Genes that are included in the LSC17 score are indicated in red. RPKM, reads per kilobase per million mapped reads. Cell Stem Cell 2017 20, 300-301DOI: (10.1016/j.stem.2017.02.010) Copyright © 2017 Elsevier Inc. Terms and Conditions