Peripheral arterial disease and methylenetetrahydrofolate reductase (MTHFR) C677T mutations: A case-control study and meta-analysis Nader Khandanpour,

Slides:

Advertisements

Similar presentations

Professionalism and the work-life balance Thomas S. Huber, MD, PhD Journal of Vascular Surgery Volume 60, Issue 4, Pages (October 2014) DOI:

Advertisements

Abdominal aortic aneurysm and abdominal wall hernia as manifestations of a connective tissue disorder George A. Antoniou, MD, George S. Georgiadis, MD,

Without prejudice Journal of Vascular Surgery

Multicenter randomized clinical trial of supervised exercise therapy with or without feedback versus walking advice for intermittent claudication Saskia.

Locoregional anesthesia for endovascular aneurysm repair

A patient with multiple paradoxical emboli

Hisato Takagi, MD, PhD, Masafumi Matsui, MD, Takuya Umemoto, MD, PhD

Michael H. Criqui, MD, MPH, Lindsey A. Ho, MPH, Julie O

Locoregional anesthesia for endovascular aneurysm repair

A percutaneous arterial closure protocol can decrease complications after endovascular interventions in vascular surgery patients Philip P. Goodney,

Mortality rates and mortality predictors in patients with symptomatic peripheral artery disease stratified according to age and diabetes Thomas Mueller,

Mohammad Hassan Murad, MD, MPH, Anas Shahrour, Nilay D

Andrew H. Stewart, FRCS, Paul S. Eyers, FRCS, Jonothan J

Frequency of cancer in patients operated on for acute peripheral arterial thrombosis and the impact on prognosis Chalotte Winther Nicolajsen, MD, Maja.

Revision using distal inflow is a safe and effective treatment for ischemic steal syndrome and pathologic high flow after access creation Thomas M. Loh,

C-reactive protein (CRP) elevation in patients with abdominal aortic aneurysm is independent of the most important CRP genetic polymorphism Stephen A.

The effect of left subclavian artery coverage on morbidity and mortality in patients undergoing endovascular thoracic aortic interventions: A systematic.

Louis L. Nguyen, MD, MBA, MPH Journal of Vascular Surgery

Joel Cooper, MD, Adam H. Power, MPhil, MD, Guy DeRose, MD, Thomas L

Long-term safety of cilostazol in patients with peripheral artery disease: The CASTLE study (Cilostazol: A Study in Long-term Effects) William R. Hiatt,

The first operation on the profunda femoris artery

Jack L. Cronenwett, MD, Christos D. Liapis, MD

Association between periodontal disease and stroke

Todd R. Vogel, MD, MPH, Viktor Y. Dombrovskiy, MD, PhD, MPH, Paul B

Without prejudice Journal of Vascular Surgery

Collateral artery from arteriovenous malformation of the rectum in a patient with peripheral artery disease Hirotomo Uchiyama, MD, Reiji Hattori, MD,

Questions remain about quality of life after abdominal aortic aneurysm repair George Peach, MRCS, Peter Holt, PhD, FRCS, Ian Loftus, MD, FRCS, Matt M.

Infected aneurysm of the thoracic aorta

Pulse palpation is an effective method for population-based screening to exclude peripheral arterial disease Louise S. Londero, MD, Jes S. Lindholt,

The impact of endovascular aneurysm repair on mortality for elective abdominal aortic aneurysm repair in England and the United States Alan Karthikesalingam,

Changing demographics in patients with vascular disease

Neurological complications after left subclavian artery coverage during thoracic endovascular aortic repair: A systematic review and meta-analysis David.

Radiation physics Journal of Vascular Surgery

Alexis Carrel's historic leap of faith

Systematic review and meta-analysis of postcarotid endarterectomy hypertension after eversion versus conventional carotid endarterectomy Serdar Demirel,

Agnes Masengu, MRCP, James McDaid, PhD, FRCS, Alexander P

Vincent L. Rowe, MD, William Lee, MD, Fred A

Hisato Takagi, MD, PhD, Takuya Umemoto, MD, PhD

Sukgu M. Han, MD, Fred A. Weaver, MD, MMM, Anthony J

A systematic review of preoperative duplex ultrasonography and arteriovenous fistula formation Chee Siong Wong, MRCSI, Nuala McNicholas, MB, Bch, Donagh.

The EXercise versus Angioplasty in Claudication Trial (EXACT): Reasons for recruitment failure and the implications for research into and treatment of.

Anthony S. Leicht, PhD, Robert G

Karen Woo, MD, Jens Eldrup-Jorgensen, MD, John W. Hallett, MD, Mark G

Simple renal cyst and abdominal aortic aneurysm

Reply Journal of Vascular Surgery

Prevalence of peripheral arterial disease and its association with smoking in a population-based study in Beijing, China Yao He, MD, PhD, Yong Jiang,

Todd R. Vogel, MD, MPH, Robin L. Kruse, PhD

Regarding “Endovascular repair of ruptured abdominal aortic aneurysms”

The risk of carotid artery stenting compared with carotid endarterectomy is greatest in patients treated within 7 days of symptoms Barbara Rantner, MD,

Jon S. Matsumura, MD, Adnan Z. Rizvi, MD Journal of Vascular Surgery

Chronic kidney disease and the short-term risk of mortality and amputation in patients hospitalized for peripheral artery disease Philippe Lacroix, MD,

Reviewer Acknowledgment

Santiago Chahwan, MD, M. Todd Miller, MD, John P. Pigott, MD, Ralph C

David L. Dawson, MD, Jennifer Meyer, RCIS, Eugene S

Contemporary outcomes of vertebral artery injury

Endovascular repair of an acute blunt popliteal artery injury

Prevalence of and risk factors for peripheral arterial disease in the patients with hypertension among Han Chinese XiaoMin Yang, MD, Kai Sun, PhD, WeiLi.

A simple subclassification of American Society of Anesthesiology III patients undergoing peripheral revascularization based on functional capacity Hasan.

Regarding “High spatial resolution magnetic resonance imaging of cystic adventitial disease of the popliteal artery” Emilie A.M. Weimar, BSc, Patrick.

The care of the patient with vascular disease

Methylenetetrahydrofolate reductase C677T polymorphism and the risk of unexplained recurrent pregnancy loss: A meta-analysis Aiguo Ren, M.D, Ph.D., Juan.

Robert J. Hinchliffe, MD, MRCS, Janet T

True Radial Artery Aneurysm: Diagnosis and Treatment

Emily Spangler, Robert W. Chang, Philip P. Goodney

Results of a single center vascular screening and education program

Saskia P. A. Nicolaï, MD, PhD, Erik J. M. Hendriks, PhD, Martin H

Association of clinical attributes and treadmill walking performance in patients with claudication due to peripheral artery disease Eric P. Brass, MD,

Adjunct endovascular interventions in carotid body tumors

The structure and processes of the Pacific Vascular Symposium 6

John F. Eidt, MD, Elliot Chaikof, MD, PhD, Anton N. Sidawy, MD, MPH

Presentation transcript:

Peripheral arterial disease and methylenetetrahydrofolate reductase (MTHFR) C677T mutations: A case-control study and meta-analysis Nader Khandanpour, MD, Gavin Willis, PhD, Felicity J. Meyer, FRCS, Matthew P. Armon, FRCS, Yoon K. Loke, MD, Anthony J.A. Wright, Paul M. Finglas, BSc, Barbara A. Jennings, PhD Journal of Vascular Surgery Volume 49, Issue 3, Pages 711-718 (March 2009) DOI: 10.1016/j.jvs.2008.10.004 Copyright © 2009 Terms and Conditions

Fig 1 A flow diagram of the study selection process. Journal of Vascular Surgery 2009 49, 711-718DOI: (10.1016/j.jvs.2008.10.004) Copyright © 2009 Terms and Conditions

Fig. 2 (A) Meta-analysis of MTHFR C677T allele frequency in patients with PAD. Odds ratios for PAD in individuals carrying the MTHFR C677T allele compared with those who were homozygous for the wile type allele. Pooled odds ratio = 1.08 (95% CI 0.98, 1.19); Z (test odds ratio differs from 1) = 1.51, P = .13; I2 (inconsistency) = 45%. (B) Meta-analysis of MTHFR C677T homozygous genotype frequency in patients with PAD. Odds rations for PAD in individuals who were homozygous for the MTHFR C677T allele compared with those who were homozygous for the wild type allele (CC vs TT). Pooled odds ratio = 1.36 (95% CI 1.10, 1.68); Z (test odds ratio differs from 1) = 2.79, P = .0052; I2 (inconsistency) = 7.6%. Journal of Vascular Surgery 2009 49, 711-718DOI: (10.1016/j.jvs.2008.10.004) Copyright © 2009 Terms and Conditions