Free flap valvular transplantation for refractory venous ulceration

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Presentation transcript:

Free flap valvular transplantation for refractory venous ulceration Raymond M. Dunn, MD, Gary M. Fudem, MD, Robert L. Walton, MD, Frederick A. Anderson, PhD, Rajwant Malhotra, MD Journal of Vascular Surgery Volume 19, Issue 3, Pages 525-531 (March 1994) DOI: 10.1016/S0741-5214(94)70081-8 Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 1 A, Fibrin staining of lipodermatosclerotic tissue area reveals pericapillary fibrin deposition. B, Flap reconstruction (same patient) biopsy at 2 years (27 months) after operation reveals no fibrin deposition. Journal of Vascular Surgery 1994 19, 525-531DOI: (10.1016/S0741-5214(94)70081-8) Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 1 A, Fibrin staining of lipodermatosclerotic tissue area reveals pericapillary fibrin deposition. B, Flap reconstruction (same patient) biopsy at 2 years (27 months) after operation reveals no fibrin deposition. Journal of Vascular Surgery 1994 19, 525-531DOI: (10.1016/S0741-5214(94)70081-8) Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 2 A, Factor VIII staining of liposclerotic tissue area reveals prominent factor VIII antibody uptake. B, Factor VIII staining of flap biopsy (same patient) at 2 years (27 months) reveals normal (minimal) antibody. Journal of Vascular Surgery 1994 19, 525-531DOI: (10.1016/S0741-5214(94)70081-8) Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 2 A, Factor VIII staining of liposclerotic tissue area reveals prominent factor VIII antibody uptake. B, Factor VIII staining of flap biopsy (same patient) at 2 years (27 months) reveals normal (minimal) antibody. Journal of Vascular Surgery 1994 19, 525-531DOI: (10.1016/S0741-5214(94)70081-8) Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 3 Hematoxylin and eosin staining of flap biopsy at 7 years reveals no histologic evidence of lipodermatosclerosis. Journal of Vascular Surgery 1994 19, 525-531DOI: (10.1016/S0741-5214(94)70081-8) Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 4 Factor VIII staining of flap biopsy at 7 years shows no increase in antibody uptake. Journal of Vascular Surgery 1994 19, 525-531DOI: (10.1016/S0741-5214(94)70081-8) Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 5 Scanning electron micrograph of bicuspid valve in circumflex scapular vein (500 μm). (Glutaraldehyde fixed specimen; original magnification ×40.) Journal of Vascular Surgery 1994 19, 525-531DOI: (10.1016/S0741-5214(94)70081-8) Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 6 Scanning electron micrograph of corrosion cast specimen of valve in circumflex scapular vein (180 μm). (Original magnification ×50.) Journal of Vascular Surgery 1994 19, 525-531DOI: (10.1016/S0741-5214(94)70081-8) Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions