Tandem Modifications of an Epoxyquinone C7N Pharmacophore

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Tandem Modifications of an Epoxyquinone C7N Pharmacophore Linquan Bai Chemistry & Biology Volume 20, Issue 7, Pages 859-860 (July 2013) DOI: 10.1016/j.chembiol.2013.07.003 Copyright © 2013 Elsevier Ltd Terms and Conditions

Figure 1 Three Families of Natural Products with Different C7N Moieties (A) Ansamycin-type natural products with 3,5-AHBA C7N moiety. (B) Aminocyclitol-type natural products with 2-epi-5-epi-valiolone as intermediate. (C) Manumycin-type natural products with epoxyquinone C7N moiety. The epoxyquinone moiety is highlighted with the square. Chemistry & Biology 2013 20, 859-860DOI: (10.1016/j.chembiol.2013.07.003) Copyright © 2013 Elsevier Ltd Terms and Conditions