Andrographis paniculata can modulate the ratio of Treg to Th17 cells in atherosclerotic rats Adi Pramono Hendrata, Kusworini Handono, Handono Kalim,

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Andrographis paniculata can modulate the ratio of Treg to Th17 cells in atherosclerotic rats Adi Pramono Hendrata, Kusworini Handono, Handono Kalim, Loeki Enggar Fitri Clinical Nutrition Experimental Volume 20, Pages 20-29 (August 2018) DOI: 10.1016/j.yclnex.2018.05.002 Copyright © 2018 The Authors Terms and Conditions

Fig. 1 The mean Treg cells in all experimental groups. Note: Data are presented in mean ± standard deviation; a p < 0.05 compared to control group; b p < 0.05 compared to atherosclerosis (Ather) group; c p < 0.05 compared to atherosclerosis + first dose of Andrographis paniculata (Ather + AP1) group; d p < 0.05 compared to atherosclerosis + second dose of Andrographis paniculata (Ather + AP2) group (%): percemtage. Clinical Nutrition Experimental 2018 20, 20-29DOI: (10.1016/j.yclnex.2018.05.002) Copyright © 2018 The Authors Terms and Conditions

Fig. 2 The mean Th17 cells in all experimental groups. Note: Data are presented in mean ± standard deviation; a p < 0.05 compared to control group; b p < 0.05 compared to atherosclerosis (Ather) group; c p < 0.05 compared to atherosclerosis + first dose of Andrographis paniculata (Ather + AP1) group; d p < 0.05 compared to atherosclerosis + second dose of Andrographis paniculata (Ather + AP2) group (%): percemtage. Clinical Nutrition Experimental 2018 20, 20-29DOI: (10.1016/j.yclnex.2018.05.002) Copyright © 2018 The Authors Terms and Conditions

Fig. 3 The mean Treg/Th17 ratio in all experimental groups. Note: Data are presented in mean ± standard deviation; a p < 0.05 compared to control group; b p < 0.05 compared to atherosclerosis (Ather) group; c p < 0.05 compared to atherosclerosis + first dose of Andrographis paniculatai (Ather + AP1) group; d p < 0.05 compared to atherosclerosis + second dose of Andrographis paniculata (Ather + AP2) group. Clinical Nutrition Experimental 2018 20, 20-29DOI: (10.1016/j.yclnex.2018.05.002) Copyright © 2018 The Authors Terms and Conditions

Fig. 4 The mean IL-17 plasma levels in all experimental groups. Note: Data are presented in mean ± standard deviation; pg/ml: picogram/mililiter. Clinical Nutrition Experimental 2018 20, 20-29DOI: (10.1016/j.yclnex.2018.05.002) Copyright © 2018 The Authors Terms and Conditions

Fig. 5 The mean IL-6 plasma levels in all experimental groups. Note: Data are presented in mean ± standard deviation; a p < 0.05 compared to control group; b p < 0.05 compared to atherosclerosis (Ather) group; c p < 0.05 compared to atherosclerosis + first dose of Andrographis paniculata (Ather + AP1) group; pg/ml: picogram/mililiter. Clinical Nutrition Experimental 2018 20, 20-29DOI: (10.1016/j.yclnex.2018.05.002) Copyright © 2018 The Authors Terms and Conditions