Effect of nominal stress on the long term friction, deformation and wear of native and glycosaminoglycan deficient articular cartilage  J. Katta, Z. Jin,

Slides:



Advertisements
Similar presentations
Efficacy of ultrasound therapy for the management of knee osteoarthritis: a systematic review with meta-analysis A. Loyola-Sánchez, J. Richardson, N.J.
Advertisements

The contribution of collagen fibers to the mechanical compressive properties of the temporomandibular joint disc  S. Fazaeli, S. Ghazanfari, V. Everts,
A. Watanabe, C. Boesch, S.E. Anderson, W. Brehm, P. Mainil Varlet 
Chondroitin sulphate: an effective joint lubricant?
T.A. Schmidt, Ph.D., R.L. Sah, M.D., Sc.D. 
Tribological and material properties for cartilage of and throughout the bovine stifle: support for the altered joint kinematics hypothesis of osteoarthritis 
Hisham A. Alhadlaq, M.S., Yang Xia, Ph.D.  Osteoarthritis and Cartilage 
Systematic assessment of growth factor treatment on biochemical and biomechanical properties of engineered articular cartilage constructs  B.D. Elder,
The epidemiology and impact of pain in osteoarthritis
P.-S. Hsu, H.-H. Lin, C.-R. Li, W.-S. Chung 
Cell deformation behavior in mechanically loaded rabbit articular cartilage 4 weeks after anterior cruciate ligament transection  S.M. Turunen, S.-K.
Associations between pre-operative radiographic changes and outcomes after total knee joint replacement for osteoarthritis  M.M. Dowsey, M. Nikpour, P.
Statistical evaluation of biomedical studies
A.C. Moore, D.L. Burris  Osteoarthritis and Cartilage 
Does land-based exercise reduce pain and disability associated with hip osteoarthritis? A meta-analysis of randomized controlled trials  M. Fransen, S.
J.B. Arnold  Osteoarthritis and Cartilage 
S.M.T. Chan, C.P. Neu, G. DuRaine, K. Komvopoulos, A.H. Reddi 
Osmolarity effects on bovine articular chondrocytes during three-dimensional culture in alginate beads  X. Xu, J.P.G. Urban, U.K. Tirlapur, Z. Cui  Osteoarthritis.
Osteoarthritis year 2011 in review: biochemical markers of osteoarthritis: an overview of research and initiatives  Y. Henrotin  Osteoarthritis and Cartilage 
Decreased proteoglycan degradation in IL-1β-treated cartilage co-cultured with TIMP-3- transduced cells  J. Mason, A. Donahue, A. Yoskowitz, D. Richardson 
Sliding motion modulates stiffness and friction coefficient at the surface of tissue engineered cartilage  S. Grad, M. Loparic, R. Peter, M. Stolz, U.
Mechanical response of articular cartilage damaged by macro cracks
The differences on extracellular matrix among each portion of meniscus
Estimation of mechanical properties of articular cartilage with MRI – dGEMRIC, T2 and T1 imaging in different species with variable stages of maturation 
Reinforcement of articular cartilage with a tissue-interpenetrating polymer network reduces friction and modulates interstitial fluid load support  B.G.
A. Hosseini, S. K. Van de Velde, M. Kozanek, T. J. Gill, A. J
L. McCann, E. Ingham, Z. Jin, J. Fisher  Osteoarthritis and Cartilage 
S.M. Hosseini, M.B. Veldink, K. Ito, C.C. van Donkelaar 
The role of cell seeding density and nutrient supply for articular cartilage tissue engineering with deformational loading  R.L. Mauck, C.C-B. Wang, E.S.
Time to be positive about negative data?
J. Avouac, M.D., L. Gossec, M.D., M. Dougados, M.D. 
Stem cell therapy for human cartilage defects: a systematic review
S. Sonne-Holm, M.D., Dr. Sci., S. Jacobsen, M.D. 
Psychological factors and their relation to osteoarthritis pain
The contribution of collagen fibers to the mechanical compressive properties of the temporomandibular joint disc  S. Fazaeli, S. Ghazanfari, V. Everts,
M. Wang, A. Radjenovic, T. W. Stapleton, R. Venkatesh, S. Williams, E
Effectiveness of thermal and athermal short-wave diathermy for the management of knee osteoarthritis: a systematic review and meta-analysis  Y. Laufer,
Hyaline cartilage cells outperform mandibular condylar cartilage cells in a TMJ fibrocartilage tissue engineering application  L. Wang, M.S., M. Lazebnik,
H. Sadeghi, D.E.T. Shepherd, D.M. Espino  Osteoarthritis and Cartilage 
Effects of sustained interstitial fluid pressurization under migrating contact area, and boundary lubrication by synovial fluid, on cartilage friction 
Removal of the superficial zone of bovine articular cartilage does not increase its frictional coefficient  R. Krishnan, M. Caligaris, R.L. Mauck, C.T.
R. A. Damion, S. S. Pawaskar, M. E. Ries, E. Ingham, S. Williams, Z
A graphic user interface for the evaluation of knee osteoarthritis (GEKO): an open- source tool for histological grading  H.E. Kloefkorn, B.Y. Jacobs,
Measurement properties of the WOMAC LK 3.1 pain scale
Meniscectomy alters the dynamic deformational behavior and cumulative strain of tibial articular cartilage in knee joints subjected to cyclic loads  Y.
Who should have a joint replacement? A plea for more ‘phronesis’
Cartilage boundary lubrication of ovine synovial fluid following anterior cruciate ligament transection: a longitudinal study  M. Atarod, T.E. Ludwig,
S. Abubacker, H.O. Ham, P.B. Messersmith, T.A. Schmidt 
A pilot study of the reproducibility and validity of measuring knee subchondral bone density in the tibia  D. Dore, BBiotech.(Hons.), C. Ding, M.D., G.
Erratum to “MMP and non-MMP-mediated release of aggrecan and its fragments from articular cartilage: a comparative study of three different aggrecan and.
D.J. Hunter  Osteoarthritis and Cartilage 
Osteoarthritis and Cartilage
S.G. Muthuri, D.F. McWilliams, M. Doherty, W. Zhang 
C. Ratzlaff, M. Koehoorn, J. Cibere, J. Kopec 
Development and preliminary evaluation of the OsteoArthritis Questionnaire (OA- Quest): a psychometric study  L. Busija, R. Buchbinder, R.H. Osborne  Osteoarthritis.
N. Frey, T. Hügle, S.S. Jick, C.R. Meier, J. Spoendlin 
Osteoarthritis year 2012 in review: biology
Knee cartilage defects in a sample of older adults: natural history, clinical significance and factors influencing change over 2.9 years  J. Carnes, O.
Location-specific hip joint space width for progression of hip osteoarthritis – Data from the Osteoarthritis Initiative  C. Ratzlaff, C. Van Wyngaarden,
R. B. Souza, C. Stehling, B. T. Wyman, M. -P. Hellio Le Graverand, X
J.F. Nishimuta, M.E. Levenston  Osteoarthritis and Cartilage 
A commentary on modelling osteoarthritis pain in small animals
Systematic review of the impact of osteoarthritis on health outcomes for comorbid disease in older people  L. Parkinson, D.L. Waters, L. Franck  Osteoarthritis.
Variations in pain and function before and after total knee arthroplasty: a comparison between Swedish and Australian cohorts  M.M. Dowsey, O. Robertsson,
Osteoarthritis year in review 2016: mechanics
Comparative study of depth-dependent characteristics of equine and human osteochondral tissue from the medial and lateral femoral condyles  J. Malda,
M. Doherty, P. Dieppe  Osteoarthritis and Cartilage 
Individuals with patellofemoral pain exhibit greater patellofemoral joint stress: a finite element analysis study  S. Farrokhi, J.H. Keyak, C.M. Powers 
A. C. Lee, W. F. Harvey, L. L. Price, L. P. K. Morgan, N. L. Morgan, C
General Information Osteoarthritis and Cartilage
Presentation transcript:

Effect of nominal stress on the long term friction, deformation and wear of native and glycosaminoglycan deficient articular cartilage  J. Katta, Z. Jin, E. Ingham, J. Fisher  Osteoarthritis and Cartilage  Volume 17, Issue 5, Pages 662-668 (May 2009) DOI: 10.1016/j.joca.2008.10.008 Copyright © 2008 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Height vernier arrangement (1a, 1b, 1c) to measure the deformation and recovery of cartilage pins after friction tests. Exaggerated schematic of the cartilage pin (1d) denoting the variables Tb, Ta and Teq measured during recovery analysis. Osteoarthritis and Cartilage 2009 17, 662-668DOI: (10.1016/j.joca.2008.10.008) Copyright © 2008 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 Effect of contact stress on the COF of native and GAG deficient articular cartilage [error bars: SE (n=6)]. Osteoarthritis and Cartilage 2009 17, 662-668DOI: (10.1016/j.joca.2008.10.008) Copyright © 2008 Osteoarthritis Research Society International Terms and Conditions

Fig. 3 Reduction, recovery and permanent deformation observed in cartilage pin samples after 7h friction tests [error bars: SE (n=6)]. Osteoarthritis and Cartilage 2009 17, 662-668DOI: (10.1016/j.joca.2008.10.008) Copyright © 2008 Osteoarthritis Research Society International Terms and Conditions

Fig. 4 Average (n=6) recovery trends for cartilage tissue on the pins while soaked in PBS postfriction tests. Osteoarthritis and Cartilage 2009 17, 662-668DOI: (10.1016/j.joca.2008.10.008) Copyright © 2008 Osteoarthritis Research Society International Terms and Conditions

Fig. 5 The amounts [mean(n=3)±SE] of sulphated sugars (GAGs) and hydroxyproline lost into the lubricant during the 7h friction tests and estimated using lubricant analysis. Osteoarthritis and Cartilage 2009 17, 662-668DOI: (10.1016/j.joca.2008.10.008) Copyright © 2008 Osteoarthritis Research Society International Terms and Conditions

Fig. 6 Surface roughness measures of native and GAG deficient (CaseABC treated) cartilage plate samples after 7h friction tests under three different contact stress levels [error bars: SE (n=6)]. Osteoarthritis and Cartilage 2009 17, 662-668DOI: (10.1016/j.joca.2008.10.008) Copyright © 2008 Osteoarthritis Research Society International Terms and Conditions

Fig. 7 Variation of friction force and the COF with applied contact stress for native cartilage in a pin-on-plate configuration with a 4mm stroke length at 1h loading time [error bars: SE (n=6)]. Osteoarthritis and Cartilage 2009 17, 662-668DOI: (10.1016/j.joca.2008.10.008) Copyright © 2008 Osteoarthritis Research Society International Terms and Conditions

Fig. 8 Effect of stroke length used in the friction tests on the COF levels of native cartilage at 3.15MPa contact stress [error bars: SE (n=6); SL – stroke length]. Osteoarthritis and Cartilage 2009 17, 662-668DOI: (10.1016/j.joca.2008.10.008) Copyright © 2008 Osteoarthritis Research Society International Terms and Conditions