Reduced diversity of the intestinal microbiota during infancy is associated with increased risk of allergic disease at school age Hans Bisgaard, MD,

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Presentation transcript:

Reduced diversity of the intestinal microbiota during infancy is associated with increased risk of allergic disease at school age Hans Bisgaard, MD, DMSc, Nan Li, MD, PhD, Klaus Bonnelykke, MD, PhD, Bo Lund Krogsgaard Chawes, MD, PhD, Thomas Skov, MSc, PhD, Georg Paludan-Müller, MSc, PhD, Jakob Stokholm, MD, Birgitte Smith, MD, Karen Angeliki Krogfelt, MSc, PhD Journal of Allergy and Clinical Immunology Volume 128, Issue 3, Pages 646-652.e5 (September 2011) DOI: 10.1016/j.jaci.2011.04.060 Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 PCA score plot colored for the DGGE at the 1- or 12-month sample. The scores from the 2 primary principal components are plotted against each other, visualizing the main systematic variation in the DGGE data. The first principal component is caused by the infant's age at sampling and explains only 3% of the total variation in the DGGE data, indicating that these data represent very little systematic variation (patterns). Journal of Allergy and Clinical Immunology 2011 128, 646-652.e5DOI: (10.1016/j.jaci.2011.04.060) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions