Volume 62, Issue 5, Pages (November 2002)

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Volume 62, Issue 5, Pages 1743-1749 (November 2002) Triglyceride, but not total cholesterol or low-density lipoprotein cholesterol levels, predict development of proteinuria Masahiko Tozawa, Kunitoshi Iseki, Chiho Iseki, Saori Oshiro, Yoshiharu Ikemiya, Shuichi Takishita Kidney International Volume 62, Issue 5, Pages 1743-1749 (November 2002) DOI: 10.1046/j.1523-1755.2002.00626.x Copyright © 2002 International Society of Nephrology Terms and Conditions

Figure 1 Quintiles of triglycerides and HDL cholesterol related to the incidence of once or more episodes of proteinuria (▪ men; □ women) and change in glomerular filtration rate (GFR; • men; ○ women).P values are given by a test for linearity across quintiles (chi-squared test for trend of proteinuria incidence and ANOVA for change in GFR). (A) P = 0.002 for men and P = 0.06 for women. (B) P = 0.02 for men and P = 0.84 for women. (C) P = 0.47 for men and P = 0.53 for women. (D) P = 0.11 for men and P = 0.22 for women. The number of persons per quintile are: (A and C) 590 to 597 men and 261 to 271 women; (panel B and D) 577 to 612 men and 258 to 289 women. Kidney International 2002 62, 1743-1749DOI: (10.1046/j.1523-1755.2002.00626.x) Copyright © 2002 International Society of Nephrology Terms and Conditions

Figure 2 Quintiles of total cholesterol and LDL cholesterol related to the incidence of one or more episodes of proteinuria (▪ men; □ women) and change in glomerular filtration rate (GFR; • men; ○ women).P values are given by a test for linearity across quintiles (chi-squared test for trend of proteinuria incidence and ANOVA for change in GFR). (A) P = 0.41 for men and P = 0.99 for women; (B) P = 0.96 for men and P = 0.99 for women; (C) P = 0.15 for men and P = 0.11 for women; (D) P = 0.09 for men and P = 0.50 for women. The number of persons per quintile are: (A and C) 579 to 611 men and 264 to 278 women; (B and D) 591 to 595 men and 270 to 273 women. Kidney International 2002 62, 1743-1749DOI: (10.1046/j.1523-1755.2002.00626.x) Copyright © 2002 International Society of Nephrology Terms and Conditions

Figure 3 Quintiles of systolic and diastolic blood pressure (BP) values related to the incidence of one or more episodes of proteinuria (▪ men; □ women) and change in glomerular filtration rate (GFR; • men; ○ women).P values are given by a test for linearity across quintiles (chi-squared test for trend of proteinuria incidence and ANOVA for change in GFR). (A) P < 0.0001 for men and P = 0.20 for women. (B) P < 0.0001 for men and P = 0.24 for women. (C) P = 0.63 for men and P = 0.64 for women. (D) P = 0.52 for men and P = 0.70 for women. The number of persons per quintile are: (A and C) 458 to 681 men and 231 to 325 women; (B and D) 426 to 694 men and 168 to 339 women. Kidney International 2002 62, 1743-1749DOI: (10.1046/j.1523-1755.2002.00626.x) Copyright © 2002 International Society of Nephrology Terms and Conditions