A disc diffusion assay for detection of class A, B and OXA-48 carbapenemases in Enterobacteriaceae using phenyl boronic acid, dipicolinic acid and temocillin 

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A disc diffusion assay for detection of class A, B and OXA-48 carbapenemases in Enterobacteriaceae using phenyl boronic acid, dipicolinic acid and temocillin  K. van Dijk, G.M. Voets, J. Scharringa, S. Voskuil, A.C. Fluit, W.C. Rottier, M.A. Leverstein-Van Hall, J. W. T. Cohen Stuart  Clinical Microbiology and Infection  Volume 20, Issue 4, Pages 345-349 (April 2014) DOI: 10.1111/1469-0691.12322 Copyright © 2014 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 1 Temocillin 30 μg disc zone diameters per β-lactamase class in 128 Enterobacteriaceae. A negative PBA and DPA synergy test and a temocillin zone diameter <10 mm are indicative of OXA-48 carbapenemase production. Clinical Microbiology and Infection 2014 20, 345-349DOI: (10.1111/1469-0691.12322) Copyright © 2014 European Society of Clinical Infectious Diseases Terms and Conditions