Volume 119, Issue 4, Pages (October 2000)

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Volume 119, Issue 4, Pages 921-928 (October 2000) Microsatellite instability is a favorable prognostic indicator in patients with colorectal cancer receiving chemotherapy Akseli Hemminki, Jukka–Pekka Mecklin, Heikki Järvinen, Lauri A. Aaltonen, Heikki Joensuu Gastroenterology Volume 119, Issue 4, Pages 921-928 (October 2000) DOI: 10.1053/gast.2000.18161 Copyright © 2000 American Gastroenterological Association Terms and Conditions

Fig. 1 Recurrence-free survival of patients with stage C CRC grouped by MSI status. All patients received adjuvant 5-FU–based chemotherapy after surgery. Only 1 of 11 MSI+ patients had a recurrence, whereas 43 of 84 MSI− patients had a relapse during follow-up. At 3 years, the difference between the MSI+ and MSI− groups is statistically significant (P = 0.020, log-rank test). Gastroenterology 2000 119, 921-928DOI: (10.1053/gast.2000.18161) Copyright © 2000 American Gastroenterological Association Terms and Conditions