Quantification of the significantly changed metabolites.

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Quantification of the significantly changed metabolites. Quantification of the significantly changed metabolites. Relative quantitative data of enriched metabolites involved in the metabolic pathways “Protein synthesis” (A) and “Alpha linolenic acid and linoleic acid metabolism” (B) identified using MetaboAnalyst software and that of representative metabolites (glucose, glucose-6-phosphate, and lactic acid) involved in glucose metabolism (C). Data were presented as fold change as compared with the average of 0.06ACR group. Boxplot of quantitative data displays the full range of variation (from minimum to maximum). *, P < 0.05 compared with the DEN group identified using ANOVA with post hoc Tukey HSD test. n.s., not significant. Xian-Yang Qin et al. Cancer Prev Res 2016;9:205-214 ©2016 by American Association for Cancer Research