Achieving Molecular Remission before Allogeneic Stem Cell Transplantation in Adult Patients with Philadelphia Chromosome–Positive Acute Lymphoblastic.

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Presentation transcript:

Achieving Molecular Remission before Allogeneic Stem Cell Transplantation in Adult Patients with Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia: Impact on Relapse and Long-Term Outcome Federico Lussana, Tamara Intermesoli, Francesca Gianni, Cristina Boschini, Arianna Masciulli, Orietta Spinelli, Elena Oldani, Manuela Tosi, Anna Grassi, Margherita Parolini, Ernesta Audisio, Chiara Cattaneo, Roberto Raimondi, Emanuele Angelucci, Irene Maria Cavattoni, Anna Maria Scattolin, Agostino Cortelezzi, Francesco Mannelli, Fabio Ciceri, Daniele Mattei, Erika Borlenghi, Elisabetta Terruzzi, Claudio Romani, Renato Bassan, Alessandro Rambaldi Biology of Blood and Marrow Transplantation Volume 22, Issue 11, Pages 1983-1987 (November 2016) DOI: 10.1016/j.bbmt.2016.07.021 Copyright © 2016 The American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Study flow. Biology of Blood and Marrow Transplantation 2016 22, 1983-1987DOI: (10.1016/j.bbmt.2016.07.021) Copyright © 2016 The American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 2 Overall survival according to alloHSCT in first remission. Biology of Blood and Marrow Transplantation 2016 22, 1983-1987DOI: (10.1016/j.bbmt.2016.07.021) Copyright © 2016 The American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 3 Cumulative incidence of (A) hematologic relapse, (B) DFS, and (C) OS by MRD group. Biology of Blood and Marrow Transplantation 2016 22, 1983-1987DOI: (10.1016/j.bbmt.2016.07.021) Copyright © 2016 The American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 4 Number of post-transplantation treatments by MRD group. Biology of Blood and Marrow Transplantation 2016 22, 1983-1987DOI: (10.1016/j.bbmt.2016.07.021) Copyright © 2016 The American Society for Blood and Marrow Transplantation Terms and Conditions