Announcements Complete Knowledge survey on-line before 9 pm Monday

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Presentation transcript:

Announcements Complete Knowledge survey on-line before 9 pm Monday Lab this week: Frog Reflexes Review information on lab webpage Upcoming Quiz (probably Friday): Thermoregulation and Glucose Homeostasis and Frog Reflexes

Acclimitization ≠ Adaptation 1st day on the job Increase body temp….. Delayed sweating via negative feedback 10th day on the job Sweating precedes changes in core body temperature and sweating is increased And salt loss in sweat is minimized Responses begin even before core temperature increases! Not just negative feedback, this is Feed Forward (requires experience). FF is evidence of Acclimitization. Acclimitization ≠ Adaptation

Acclimatization & Feedforward Deviations from set point are minimized Learned (by experience) Anticipates changes of a physiological parameter Response begins before there is a change in the physiological variable Minimizes fluctuations

~37oC Be able to explain the physiology in each of these situations with a detailed diagram of negative feedback responses!

Heat Stroke Blood Pressure Blood Flow to brain Cutaneous vasodilation Sympathetic outflow Blood Pressure Blood Flow to brain Disrupted function of neurons Cutaneous vasodilation Sweating

Positive feedback Inherently unstable Examples of Positive Feedback in Physiology Heat stroke formation of blood clot menstrual cycling of female sex hormone concentrations generation of action potentials in nerve fibers uterine contractions during childbirth Each of these examples terminate naturally (self limiting) Homeostasis is achieved by negative feedback loops: the integrator detects deviations from set point and orchestrates responses produced by effectors that return the parameter toward the set point.