Marjolein Wensing, MDa, Jaap H. Akkerdaas, MScb, W

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Presentation transcript:

IgE to Bet v 1 and profilin: Cross-reactivity patterns and clinical relevance Marjolein Wensing, MDa, Jaap H. Akkerdaas, MScb, W.Astrid van Leeuwen, BScb, Steven O. Stapel, PhDb, Carla A.F.M. Bruijnzeel- Koomen, MDa, Rob C. Aalberse, PhDb, Bert J.E.G. Bast, PhDc, André C. Knulst, MDa, Ronald van Ree, PhDb Journal of Allergy and Clinical Immunology Volume 110, Issue 3, Pages 435-442 (September 2002) DOI: 10.1067/mai.2002.126380 Copyright © 2002 Mosby, Inc. Terms and Conditions

Fig. 1 Correlations between specific IgE titers of Bet v 1, profilin, and 14 plant-derived foods calculated by using the Spearman rank test. (Figure continued on next page) Journal of Allergy and Clinical Immunology 2002 110, 435-442DOI: (10.1067/mai.2002.126380) Copyright © 2002 Mosby, Inc. Terms and Conditions

Fig. 2 Number of positive test results and case histories to 14 plant-derived foods subdivided according to Bet v 1 sensitization, profilin sensitization, or both. Significant associations (tested by means of χ2 analysis) are indicated by arrows . Yellow cells indicate Bet v 1-related data, and blue cells indicate profilin-related data. CH, Case history. Journal of Allergy and Clinical Immunology 2002 110, 435-442DOI: (10.1067/mai.2002.126380) Copyright © 2002 Mosby, Inc. Terms and Conditions

Fig. 3 RAST inhibition assays of 4 patients. *Patients 11 and 53 are also sensitized to latex. RAST values are given in brackets. Green bars, Inhibition with grass pollen extract; red bars, inhibition with birch pollen extract; orange bars, inhibition with proteinase K-treated grass pollen extract (CCD); blue bars, inhibition with latex extract. Journal of Allergy and Clinical Immunology 2002 110, 435-442DOI: (10.1067/mai.2002.126380) Copyright © 2002 Mosby, Inc. Terms and Conditions

Fig. 3 RAST inhibition assays of 4 patients. *Patients 11 and 53 are also sensitized to latex. RAST values are given in brackets. Green bars, Inhibition with grass pollen extract; red bars, inhibition with birch pollen extract; orange bars, inhibition with proteinase K-treated grass pollen extract (CCD); blue bars, inhibition with latex extract. Journal of Allergy and Clinical Immunology 2002 110, 435-442DOI: (10.1067/mai.2002.126380) Copyright © 2002 Mosby, Inc. Terms and Conditions