CRF48_01B CRF48_01B (1995.9, ) (1999.7, ) CRF33_01B . CRF33_01B

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Presentation transcript:

CRF48_01B CRF48_01B 1999.4 (1995.9, 2002.9) 2002.2 (1999.7, 2004.5) CRF33_01B . CRF33_01B 1994.0 (1990.4, 1997.3) 1992.3 (1988.3, 1996.2) CRF48_01B CRF33_01B Thailand CRF01 _AE African CRF01_AE CRF48_01B CRF33_01B Thailand CRF01 _AE African CRF01_AE I I+IIIa gag (HXB2: 790-2052) gag-env concatenated (HXB2: 790-2052; 6882-7637) CRF01_AE region CRF01_AE region Thailand CRF01_AE Thailand CRF01_AE 1982.3 (1976.9, 1986.8) 1982.0 (1976.7, 1986.4) African CRF01_AE African CRF01_AE 1976.4 (1969.1, 1983.6) 1974.2 (1965.1, 1982.2) 1980 1990 2000 2010 1970 1980 1990 2000 2010 1970 CRF48_01B 2001.9 (1998.8, 2004.8) CRF33_01B 1993.7 (1989.5, 1997.5) CRF48_01B IIa+IIb CRF33_01B gag-pol concatenated (HXB2: 2065-2374, 2541-2840) Subtype B’ region B’ B (US-European) Supplemental Fig. S2. Li et al. 1980 1990 2000 2010 1970

Supplemental Digital Content 2 – Figure 2 Supplemental Digital Content 2 – Figure 2. Maximum clade credibility (MCC) trees based on different genome regions obtained by Bayesian MCMC analysis. (A) Region I: gag region (HXB2: 790-2052); (B) Region I+IIIa: gag-env region (concatenated) (HXB2: 790-2052; 6882-7637); (C) Region IIa+IIb: gag-env region (concatenated) (HXB2: 2065-2374; 2541-2840). The tips of the tree correspond to year of sampling, and the branch lengths reflect the mean of the posterior probability density. The estimated tMRCAs for CRF33_01B and CRF48_01B and their parental CRF01_AE lineages are shown.