Vesicles Spread Susceptibility to Phages

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Vesicles Spread Susceptibility to Phages Gal Ofir, Rotem Sorek Cell Volume 168, Issue 1, Pages 13-15 (January 2017) DOI: 10.1016/j.cell.2016.12.035 Copyright © 2017 Elsevier Inc. Terms and Conditions

Figure 1 Extracellular Vesicles Transfer Phage Receptors Susceptible cells carry the phage receptors on their outer envelopes. In this study, membrane proteins and cell wall components are shown to travel on extracellular membrane vesicles, whose generation is enhanced by phage induced lysis. These vesicles transfer the phage receptors to resistant cells, making them transiently susceptible to phage adsorption and infection. This can serve as an avenue for phage-mediated horizontal gene transfer to non-host species. Cell 2017 168, 13-15DOI: (10.1016/j.cell.2016.12.035) Copyright © 2017 Elsevier Inc. Terms and Conditions