Osteoarthritis pain mechanisms: basic studies in animal models

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Osteoarthritis pain mechanisms: basic studies in animal models R.-X. Zhang, K. Ren, R. Dubner  Osteoarthritis and Cartilage  Volume 21, Issue 9, Pages 1308-1315 (September 2013) DOI: 10.1016/j.joca.2013.06.013 Copyright © 2013 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Diagram illustrating mechanisms of OA-induced pain. Bioactive chemicals are involved in OA-induced pain at peripheral, spinal and supraspinal levels. IL-13, interleukin-13; IL-17, interleukin-17; IL-1α/β, interleukin alpha/beta. Osteoarthritis and Cartilage 2013 21, 1308-1315DOI: (10.1016/j.joca.2013.06.013) Copyright © 2013 Osteoarthritis Research Society International Terms and Conditions