Platelet-derived chemokines: New targets to treat liver fibrosis

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Platelet-derived chemokines: New targets to treat liver fibrosis Oriol Morales-Ibanez, Ramón Bataller Journal of Hepatology Volume 54, Issue 3, Pages 581-583 (March 2011) DOI: 10.1016/j.jhep.2010.09.016 Copyright © 2010 European Association for the Study of the Liver Terms and Conditions

Fig. 1 CC and CXC Chemokine ligands and their receptors. Nomenclature: GRO alpha (CXCL1), GRO beta (CXCL2), GRO gamma (CXCL3), ENA78 (epithelial-derived neutrophil-activating peptide 78, CXCL5), GCP2 (granulocyte chemoattractant protein 2, CXCL6), NAP2 (neutrophil-activating protein 2, CXCL7), IL8 (interleukin 8, CXCL8), MIG (monokine induced by gamma interferon, CXCL9), IP10 (interferon-gamma-induced protein 10, CXCL10), I-TAC (interferon γ-inducible T cell α-chemoattractant, CXCL11), PF4 (platelet factor 4, CXCL4), SDF1 (stromal-derived factor 1, CXCL12), BCA1 (B cell-attracting chemokine 1, CXCL13), BRAK (breast and kidney expressed chemokine, CXCL14), Lungkine (CXCL15), SexCKine (CXCL16), Lymphotactin (XCL1), Fractalkine (CX3CL1), IL8RB (interleukin 8 receptor beta, CXCR2), IL8RA (interleukin 8 receptor alpha, CXCR1), BLR1 (Burkitt lymphoma receptor 1, CXCR5), TECK (thymus-expressed chemokine, CCL25), SLC (secondary lymphoid chemokine, CCL21), MIP3α (macrophage inflammatory protein 3, liver activation regulated protein (LARC), CCL20), MIP1α (macrophage inflammatory protein 1), MIP1β (macrophage inflammatory protein 2), RANTES (regulated upon activation normal T cell expressed and secreted, CCL5), TARC (thymus and activation-regulated chemokine, CCL17), MDC (macrophage-derived chemokine, CCL22), MCP3 (monocyte chemoattracting protein 3, CCL7), MCP2 (monocyte chemoattracting protein 2, CCL8), Eotaxin (CCL11), HCC2 (human CC chemokine 2, CCL15), MCP1 (monocyte chemoattracting protein 1, CCL2), MCP5 (monocyte chemoattracting protein 5, CCL12), HCC1 (human CC chemokine 1, CCL14), LEC (liver-expressed chemokine 2, CCL16). Journal of Hepatology 2011 54, 581-583DOI: (10.1016/j.jhep.2010.09.016) Copyright © 2010 European Association for the Study of the Liver Terms and Conditions