5-5 NOTES: TRANSLATION RNA  PROTEIN

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Presentation transcript:

5-5 NOTES: TRANSLATION RNA  PROTEIN

Remember…. Flow of information is: DNA  RNA  Protein Called the Central Dogma

Translation Definition: The process of assembling proteins from the mRNA message. Location: ribosome Molecules involved: mRNA, tRNA, rRNA

BEFORE TRANSLATION TAKES PLACE DNA has the codes to make a protein

BEFORE TRANSLATION TAKES PLACE DNA has the codes to make a protein mRNA is transcribed carrying the copy of information to make a protein

BEFORE TRANSLATION TAKES PLACE DNA has the codes to make a protein mRNA is transcribed carrying the copy of information to make a protein mRNA leaves the nucleus and binds to a ribosome.

Steps of Translation Step 1- Initiation Ribosome assembles at the start codon of mRNA (methionine) AUG

Steps of Translation Step 2- Elongation The ribosome moves down the mRNA one codon at a time and tRNA adds an amino acid

Steps of Translation Step 2 Elongation Peptide bonds are formed between the amino acids creating a growing polypeptide. Protein molecule

Steps of Translation Step 3- Termination The process continues until a stop codon is reached. Ribosome falls apart releasing the newly made protein stop codon Protein molecule

Proteins 20 different amino acids are used to create thousands of different proteins.

Proteins 20 different amino acids are used to create thousands of different proteins. The # and order of these AA determines which protein they become.

How does tRNA know which AA to bring?

tRNA reads Codons A Codon is 3 nucleotides long on mRNA

tRNA reads Codons A Codon is 3 nucleotides long on mRNA Each codon codes for an Amino Acid

tRNA reads Codons A Codon is 3 nucleotides long on mRNA Each codon codes for an Amino Acid Certain codons signal start and stop.

Genetic Code The genetic code is a set of rules for translation

How to use the Genetic Code (Translating) Use the three letters of the codon 1st letter on left side to find row 2nd letter on top to find column 3rd letter on right to narrow down to one AA AAC

Transcribe then translate this piece of DNA DNA: T-A-C-A-A-T- A-G-G-G-T- C mRNA: AA:

Make and fill in chart Translation Transcription location Molecule made Molecules involved