A prospective comparison of galactomannan in bronchoalveolar lavage fluid for the diagnosis of pulmonary invasive aspergillosis in medical patients under.

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A prospective comparison of galactomannan in bronchoalveolar lavage fluid for the diagnosis of pulmonary invasive aspergillosis in medical patients under intensive care: comparison with the diagnostic performance of galactomannan and of (1→ 3) – β – d- glucan chromogenic assay in serum samples J. Acosta, M. Catalan, A. del Palacio-Peréz-Medel, D. Lora, J.-C. Montejo, M.-S. Cuetara, M.-D. Moragues, J. Ponton, A. del Palacio Clinical Microbiology and Infection Volume 17, Issue 7, Pages 1053-1060 (July 2011) DOI: 10.1111/j.1469-0691.2010.03357.x Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 1. Area under the curve (AUC) of receiver-operating curves (ROC) for: (a) all invasive aspergillosis (IA) cases, proven and probable; (b) proven IA cases; and (c) all invasive fungal disease cases (IA and P. jirovecii pneumonia). In case of IA (proven and probable), the AUC for GM in BAL was significantly higher than GM and BG in serum (p 0.0258 and p 0.0322, respectively). In cases of proven IA, there was no significant difference between the AUC for GM in BAL when compared with the AUC for GM and BG in serum (p 0.203 and p 0.159, respectively). Clinical Microbiology and Infection 2011 17, 1053-1060DOI: (10.1111/j.1469-0691.2010.03357.x) Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions