Small Molecules Take a Big Step by Converting Fibroblasts into Neurons

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Presentation transcript:

Small Molecules Take a Big Step by Converting Fibroblasts into Neurons Kimberley Babos, Justin K. Ichida  Cell Stem Cell  Volume 17, Issue 2, Pages 127-129 (August 2015) DOI: 10.1016/j.stem.2015.07.018 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 1 Summary of the Chemical Conversion of Fibroblasts into Neurons Two different small-molecule cocktails convert fibroblasts into vGlut1+ or GABA+ neurons, neither one transiting cells through a neural progenitor state. Certain chemicals destabilize the fibroblast state while others seem to induce neurogenesis. (Image credit: Kristen Chen.) Cell Stem Cell 2015 17, 127-129DOI: (10.1016/j.stem.2015.07.018) Copyright © 2015 Elsevier Inc. Terms and Conditions

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