Meta-Analysis of Effects of Digoxin on Survival in Patients with Atrial Fibrillation or Heart Failure: An Update  Mate Vamos, MD, PhD, Julia Wiebke Erath,

Slides:



Advertisements
Similar presentations
Date of download: 6/1/2016 Copyright © The American College of Cardiology. All rights reserved. From: Beta-Blockers and Outcome in Heart Failure and Atrial.
Advertisements

Atrial Fibrillation and Heart Failure Andrew A. Grace, MB, PhD, FRCP Heart Failure Clinics Volume 9, Issue 4, (October 2013) DOI: /j.hfc
Dual-site right ventricular and left ventricular pacing in a patient with left ventricular systolic dysfunction and atrial fibrillation using a standard.
Usefulness of Platelet Response to Clopidogrel by Point-of-Care Testing to Predict Bleeding Outcomes in Patients Undergoing Percutaneous Coronary Intervention.
Patient request for pharmacist counseling and satisfaction: Automated prescription delivery system versus regular pick-up counter Jan D. Hirsch, PhD Journal.
CHA2DS2-VASC and CHADS2 Scores Predict Adverse Clinical Events in Patients With Pacemakers and Sinus Node Dysfunction Independent of Atrial Fibrillation 
Relation of Heart Rate at Rest and Long-Term (>20 Years) Death Rate in Initially Healthy Middle-Aged Men  Xavier Jouven, MD, PhD, Jean Philippe Empana,
Colloquium on Therapy of Right Heart Failure
Outcomes of a Pharmacoinvasive Strategy for Successful Versus Failed Fibrinolysis and Primary Percutaneous Intervention in Acute Myocardial Infarction.
Meta-Analysis of Transcatheter Aortic Valve Replacement Versus Surgical Aortic Valve Replacement in Patients With Severe Aortic Valve Stenosis  Ashok.
Kiran Sidhu, MD, FRCPC, Anthony Tang, MD, FRCPC 
Long-Term Population-Based Cerebral Ischemic Event and Cognitive Outcomes of Direct Oral Anticoagulants Compared With Warfarin Among Long-term Anticoagulated.
Outcome of Noncardiac and Nonvascular Surgery in Patients With Mechanical Heart Valves  Murat Biteker, MD, Ahmet İlker Tekkeşin, MD, Mehmet Mustafa Can,
Volume 14, Issue 8, Pages e255-e269 (August 2017)
Community-Based Mind–Body Meditative Tai Chi Program and Its Effects on Improvement of Blood Pressure, Weight, Renal Function, Serum Lipoprotein, and.
New-onset Atrial Fibrillation Predicts Heart Failure Progression
Admission heart rate and in-hospital outcomes in patients hospitalized for heart failure in sinus rhythm and in atrial fibrillation  Anh L. Bui, MD, Maria.
Meta-Analysis of Dietary Glycemic Load and Glycemic Index in Relation to Risk of Coronary Heart Disease  Jia-Yi Dong, BSc, Yong-Hong Zhang, MD, PhD, Peiyu.
Manuel J. Antunes, MD, PhD, DSc 
Frontiers of anticoagulation therapy for atrial fibrillation
Differences and trends in stroke prevention anticoagulation in primary care vs cardiology specialty management of new atrial fibrillation: The Retrospective.
Moderate Pulmonary Embolism Treated With Thrombolysis (from the “MOPETT” Trial)  Mohsen Sharifi, MD, Curt Bay, PhD, Laura Skrocki, DO, Farnoosh Rahimi,
Comparison of Bare-Metal Stents and Drug-Eluting Stents in Coronary Ostial Lesions (from the National Heart, Lung, and Blood Institute Dynamic Registry) 
Contribution of Three-Dimensional Transesophageal Echocardiography to Diagnosis and Management of Thrombosis of a St. Jude Mechanical Prosthesis in the.
Influence of Body Mass Index on Long-Term Survival After Cardiac Catheterization  Barak Zafrir, MD, Ronen Jaffe, MD, Ronen Rubinshtein, MD, Basheer Karkabi,
EMPA-REG OUTCOME: The Endocrinologist's Point of View
Alfred A. Bartolucci, PhD, Michal Tendera, MD, George Howard, DrPH 
Two-Year Clinical Outcomes After Enhanced External Counterpulsation (EECP) Therapy in Patients With Refractory Angina Pectoris and Left Ventricular Dysfunction.
Volume 143, Issue 1, Pages (January 2013)
Tsung-Yu Tsai, MD, Yu-Chen Huang, MD 
Role of the CHADS2 Score in Acute Coronary Syndromes
Renato D. Lopes, MD, PhD, Li Li, MS, Christopher B
Masaya Koshizaka, MD, PhD, Renato D. Lopes, MD, PhD, MHS, L
Richard V. Milani, MD, Carl J. Lavie, MD, Robert M
Trends in Comorbidity, Disability, and Polypharmacy in Heart Failure
CHA2DS2-VASc Score Is Directly Associated with the Risk of Pulmonary Embolism in Patients with Atrial Fibrillation  Walid Saliba, MD, MPH, Gad Rennert,
Prognostic Importance of Low Admission Serum Creatinine Concentration for Mortality in Hospitalized Patients  Charat Thongprayoon, MD, Wisit Cheungpasitporn,
Alexander M. Walker, MD, DrPH, Dimitri Bennett, MD, MPH  Heart Rhythm 
Trend in Mortality after Stroke with Atrial Fibrillation
Alexander M. Walker, MD, DrPH, Dimitri Bennett, MD, MPH  Heart Rhythm 
All-cause Mortality Associated with TNF-α Inhibitors in Rheumatoid Arthritis: A Meta- Analysis of Randomized Controlled Trials  Lucile Poiroux, MD, Yannick.
Gregory Y.H. Lip, MD, Jonathan L. Halperin, MD, Hung-Fat Tse, MD, PhD 
Building a bioartificial heart: A 3-song saga
History of Thyroid Disorders in Relation to Clinical Outcomes in Atrial Fibrillation  Helene Bruere, MD, Laurent Fauchier, MD, PhD, Anne Bernard Brunet,
Murray H. Kwon, MD  The Journal of Thoracic and Cardiovascular Surgery 
Perceived Complexity of Various Liver Resections: Results of a Survey of Experts with Development of a Complexity Score and Classification  Major K. Lee,
Form ever follows function
William M. DeCampli, MD, PhD 
Multilevel data analysis: What? Why? How?
Philippe Menasché, MD, PhD 
Volume 14, Issue 8, Pages e255-e269 (August 2017)
Impact of prior hospital mortality versus surgical volume on mortality following surgery for congenital heart disease  Matthew E. Oster, MD, Matthew J.
Sinus node structural changes in patients with long-standing chronic atrial fibrillation  Aquilino Hurlé, MD, PhD, Vicente Climent, MD, PhD, Damian Sánchez-Quintana,
Use of Diuretics in Heart Failure: A Precarious Balance
Screening for atrial fibrillation with automated blood pressure measurement: Research evidence and practice recommendations  Willem J. Verberk, Stefano.
Erratum The American Journal of Human Genetics
Antidepressant use and risk for mortality in 121,252 heart failure patients with or without a diagnosis of clinical depression  Corline Brouwers, Stefan.
Steroid-antiviral Treatment Improves the Recovery Rate in Patients with Severe Bell's Palsy  Ho Yun Lee, MD, Jae Yong Byun, MD, Moon Suh Park, MD, Seung.
Table of contents The Journal for Nurse Practitioners
International Journal of Cardiology
Unusual severe hemodynamic failure associated with standard dose of intravenous flecainide for pharmacological cardioversion of atrial fibrillation  Aref.
Meta-analysis of randomized trials on the efficacy of posterior pericardiotomy in preventing atrial fibrillation after coronary artery bypass surgery 
Clinical benefit of adenosine as an adjunct to reperfusion in ST-elevation myocardial infarction patients: An updated meta-analysis of randomized controlled.
Tsung-Yu Tsai, MD, Yu-Chen Huang, MD 
Jeffrey H. Shuhaiber, MD, Jeff Moore, MS, David B. Dyke, MD 
The future of cardiac surgery training: A survival guide
What Is Chronic Cough? Terminology
Commentary: Judgment day: Should you add atrial fibrillation ablation?
Appropriate Use Criteria for coronary revascularization in patients with stable ischemic heart disease: What the surgeon needs to know  Harold L. Lazar,
Has mortality from acute renal failure decreased
Presentation transcript:

Meta-Analysis of Effects of Digoxin on Survival in Patients with Atrial Fibrillation or Heart Failure: An Update  Mate Vamos, MD, PhD, Julia Wiebke Erath, MD, Alexander Philipp Benz, MD, Renato Delascio Lopes, MD, PhD, Stefan Hans Hohnloser, MD  American Journal of Cardiology  Volume 123, Issue 1, Pages 69-74 (January 2019) DOI: 10.1016/j.amjcard.2018.09.036 Copyright © 2018 Terms and Conditions

American Journal of Cardiology 2019 123, 69-74DOI: (10.1016/j.amjcard.2018.09.036) Copyright © 2018 Terms and Conditions

Figure 1 Forest plot of studies describing the effects of digoxin on mortality, both for studies in atrial fibrillation and heart failure. Data had been adjusted for potential confounders in the various studies. American Journal of Cardiology 2019 123, 69-74DOI: (10.1016/j.amjcard.2018.09.036) Copyright © 2018 Terms and Conditions

Figure 2 Sensitivity analysis of studies which provided data on digoxin dosing and/or serum levels: Forest-plot. American Journal of Cardiology 2019 123, 69-74DOI: (10.1016/j.amjcard.2018.09.036) Copyright © 2018 Terms and Conditions

Figure 3 Sensitivity analysis of new digoxin users: Forest-plot. American Journal of Cardiology 2019 123, 69-74DOI: (10.1016/j.amjcard.2018.09.036) Copyright © 2018 Terms and Conditions

Figure 4 Sensitivity analysis of studies published after 2015: Forest-plot. American Journal of Cardiology 2019 123, 69-74DOI: (10.1016/j.amjcard.2018.09.036) Copyright © 2018 Terms and Conditions