Volume 153, Issue 3, Pages 711-722 (September 2017) Prebiotics Reduce Body Fat and Alter Intestinal Microbiota in Children Who Are Overweight or With Obesity  Alissa C. Nicolucci, Megan P. Hume, Inés Martínez, Shyamchand Mayengbam, Jens Walter, Raylene A. Reimer  Gastroenterology  Volume 153, Issue 3, Pages 711-722 (September 2017) DOI: 10.1053/j.gastro.2017.05.055 Copyright © 2017 AGA Institute Terms and Conditions

Figure 1 Change in body composition in the prebiotic (n = 22) and placebo (n = 19) groups over the 16-week intervention represented by mean ± SEM. *P < .05 and †P < .01 with independent t-test between the 2 groups. Gastroenterology 2017 153, 711-722DOI: (10.1053/j.gastro.2017.05.055) Copyright © 2017 AGA Institute Terms and Conditions

Figure 2 Heat map of the Spearman rank correlations between biological and gut microbial outcomes. Correlations were performed on the change in outcomes over the 16-week intervention. *P < .05 and †P < .01. BF, body fat; BMI, body mass index; HDL, high-density lipoprotein; LDL, low-density lipoprotein; CRP, C-reactive protein; IL, interleukin; TNFα, tumor necrosis factor alpha; UDCA, ursodeoxycholic acid; DCA, deoxycholic acid; CA, cholic acid; CDCA, chenodeoxycholic acid; HDCA, hyodeoxycholic acid; LCA, lithocholic acid; FA, fecal bile acids. Gastroenterology 2017 153, 711-722DOI: (10.1053/j.gastro.2017.05.055) Copyright © 2017 AGA Institute Terms and Conditions