All-cause Mortality Associated with TNF-α Inhibitors in Rheumatoid Arthritis: A Meta- Analysis of Randomized Controlled Trials Lucile Poiroux, MD, Yannick.

Slides:

Advertisements

Similar presentations

Low-Dose Aspirin in Patients with Stable Cardiovascular Disease: A Meta-analysis Jeffrey S. Berger, MD, MS, David L. Brown, MD, Richard C. Becker, MD The.

Advertisements

Severe Tuberculosis Sepsis in an Immunocompetent Patient

Paul D. Stein, MD, Fadi Matta, MD, Mary J. Hughes, DO

Pneumothorax Recurrence Related to High-speed Lift

Bleeding Toes in Diabetic Neuropathy

Pierre Loulergue, MD, MSc, Agnès Guerre, MD

Amay Parikh, MD, MBA, MS, Kunal Gupta, MD, MBA, Alan C

The Effect of Smoking on the Risk of Sciatica: A Meta-analysis

Sexuality The American Journal of Medicine

Alternative Smoking Cessation Aids: A Meta-analysis of Randomized Controlled Trials Mehdi Tahiri, MD, Salvatore Mottillo, MD, Lawrence Joseph, PhD, Louise.

Not Just Another Flare: Acute Polyarthritis in Rheumatoid Arthritis

An Unusual Cause of Leg Ulcerations

Impact of More Restrictive Blood Transfusion Strategies on Clinical Outcomes: A Meta- analysis and Systematic Review Shelley R. Salpeter, MD, Jacob S.

Richard V. Milani, MD, Carl J. Lavie, MD, Robert M

Comparative Effectiveness Research and Medical Informatics

Bleeding Toes in Diabetic Neuropathy

Alternative Smoking Cessation Aids: A Meta-analysis of Randomized Controlled Trials Mehdi Tahiri, MD, Salvatore Mottillo, MD, Lawrence Joseph, PhD, Louise.

Pierre Loulergue, MD, MSc, Agnès Guerre, MD

Scientific and Organizational Collaboration in Comparative Effectiveness Research: The VA Cooperative Studies Program Model Grant D. Huang, MPH, PhD,

Matthew I. Worthley, MBBS, PhD, FRACP, Fiona M

One Appendix, Two Different Pains

Systematic Review of the Mediterranean Diet for Long-Term Weight Loss

Systematic Review and Meta-analysis of Adverse Events of Low-dose Aspirin and Clopidogrel in Randomized Controlled Trials Kenneth R. McQuaid, MD, Loren.

Leslie R. Harrold, MD, MPH, Daniel Peterson, MS, Ashley J

A Randomized Controlled Trial of a Community-based Behavioral Counseling Program Craig A. Johnston, PhD, Stephanie Rost, MS, RD, Karen Miller-Kovach,

Thomas E. MacMillan, MD, MSc, Terence Tang, MD, Rodrigo B

Epidemiology of Myelodysplastic Syndromes

Marc Carrier, MD, MSc, Alok A

Robert Goulden, MBBS, MSc, MPhil, MA The American Journal of Medicine

Peter M. Farrehi, MD, Kristen R. Clore, OTRL, J

Noninfective Endocarditis in Rheumatoid Arthritis

Artificial Hyperparathyroidism—Think Twice Before Taking Your Blood Sample Daniel Foehring, MD, Lars Moeller, MD, Dagmar Fuhrer, MD, Harald Lahner, MD

The Reply The American Journal of Medicine

Jessica L. Lee, MD, MS, Esther S. Oh, MD, Rebecca W. Lee, MD, Thomas E

Metabolic Syndrome and Sexual Function in Postmenopausal Women

The Recent History of Acupuncture

Gout in African Americans

Cardiovascular Risks of Exogenous Testosterone Use Among Men: A Systematic Review and Meta-Analysis G. Caleb Alexander, MD, MS, Geetha Iyer, MBBS, Eleanor.

Carlos Aguilar, MD, Valentin del Villar, MD

James H. O'Keefe, MD, Robert Vogel, MD, Carl J

A Diagnostic Dilemma in a Patient with Polyarthritis

The Reply The American Journal of Medicine

Does Methylphenidate Reduce the Symptoms of Chronic Fatigue Syndrome?

Disseminated Zoster After Trauma in an Immunocompetent Patient

Seizure with Acute Pulmonary Infiltrates

Independent of Cirrhosis, Hepatocellular Carcinoma Risk Is Increased with Diabetes and Metabolic Syndrome Allison J. Kasmari, MD, Amy Welch, MD, MSN,

Geographic Tongue The American Journal of Medicine

Sharan Prakash Sharma, MD, Karleung Siu, MD

To Reduce Stroke with PFO Closure, Respect the Shunt

Effect of Folic Acid, with or without Other B Vitamins, on Cognitive Decline: Meta- Analysis of Randomized Trials David S. Wald, MA, MRCP, MD, Anuradhani.

John-Michael Gamble, BScPharm, MSc, Dean T. Eurich, PhD, Thomas J

Steroid-antiviral Treatment Improves the Recovery Rate in Patients with Severe Bell's Palsy Ho Yun Lee, MD, Jae Yong Byun, MD, Moon Suh Park, MD, Seung.

One-way Versus Two-way Text Messaging on Improving Medication Adherence: Meta- analysis of Randomized Trials David S. Wald, MD, FRCP, Shahena Butt, MSc,

Purple Urinary Bag Syndrome

A Review of Learner Impact on Faculty Productivity

A Post-cure Complication

Sister Mary Joseph's Node

Plasma Lactescence in Acute Pancreatitis

Primary Care Management of Skin Abscesses Guided by Ultrasound

Trends in Prolonged Hospitalizations in the United States from 2001 to 2012: A Longitudinal Cohort Study Lauren Doctoroff, MD, Douglas J. Hsu, MD, Kenneth.

Rebecca D. Chason, Joan S. Reisch, PhD, Don C. Rockey, MD

Falls in Older Adults: Risk Assessment, Management and Prevention

Has mortality from acute renal failure decreased

Emily G. McDonald, MD, MSc, Ramy R. Saleh, MD, Todd C. Lee, MD, MPH

Longer Lengths of Stay and Higher Risk of Mortality among Inpatients of Physicians with More Years in Practice William N. Southern, MD, MS, Eran Y. Bellin,

Toward a More Responsible News Media

Bijin Thajudeen, MD, Mario F. Rubin, MD

David Tian, MD, Ram Jhingan Mohan, MD, Gary Stallings, MD

Preoperative Thienopyridine Use and Outcomes after Surgery: A Systematic Review Anita G. Au, MD, Sumit R. Majumdar, MD MPH, Finlay A. McAlister, MD MSc

Hypophosphatemia: Diagnostic Significance in Legionnaires’ Disease

Presentation transcript:

All-cause Mortality Associated with TNF-α Inhibitors in Rheumatoid Arthritis: A Meta- Analysis of Randomized Controlled Trials Lucile Poiroux, MD, Yannick Allanore, MD, PhD, André Kahan, MD, PhD, Jérôme Avouac, MD, PhD The American Journal of Medicine Volume 128, Issue 12, Pages 1367-1373.e1 (December 2015) DOI: 10.1016/j.amjmed.2015.07.020 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 1 Flow diagram of articles evaluated for inclusion and exclusion. RA = rheumatoid arthritis. The American Journal of Medicine 2015 128, 1367-1373.e1DOI: (10.1016/j.amjmed.2015.07.020) Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 2 Forest plot of trials comparing tumor necrosis factor-α inhibitors to comparators for the risk of all-cause mortality in patients with rheumatoid arthritis. Heterogeneity: Q = 7.87; df = 22, P = .99, I2 < 25%. The American Journal of Medicine 2015 128, 1367-1373.e1DOI: (10.1016/j.amjmed.2015.07.020) Copyright © 2015 Elsevier Inc. Terms and Conditions