Assessment of cardiovascular function by combining clinical data with a computational model of the cardiovascular system Koichi Sughimoto, MD, PhD, Fuyou.

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Presentation transcript:

Assessment of cardiovascular function by combining clinical data with a computational model of the cardiovascular system Koichi Sughimoto, MD, PhD, Fuyou Liang, PhD, Yoshiharu Takahara, MD, PhD, Kenji Mogi, MD, PhD, Kenji Yamazaki, MD, PhD, Shu Takagi, PhD, Hao Liu, PhD The Journal of Thoracic and Cardiovascular Surgery Volume 145, Issue 5, Pages 1367-1372 (May 2013) DOI: 10.1016/j.jtcvs.2012.07.029 Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Distribution of the patients according to the estimated Elva/Elva0 and Elvp/Elvp0. The point where Elva/Elva0 = 1 is set to be the normal point. The patients with Elva/Elva0 < 1 are classified as having systolic dysfunction whereas those with Elvp/Elvp0 > 1 are classified as having diastolic dysfunction. Quadrant I: normal systolic function and degenerated diastolic function, quadrant II: an optimal ventricular functional state, quadrant III: normal diastolic function and impaired systolic function, and quadrant IV: both systolic and the diastolic functions are abnormal. Elva/Elva0, Normalized left ventricular active elastance; Elvp/Elvp0, normalized left ventricular passive elastance. The Journal of Thoracic and Cardiovascular Surgery 2013 145, 1367-1372DOI: (10.1016/j.jtcvs.2012.07.029) Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Model-predicted left ventricular pressure–volume loops for the patients studied. The Journal of Thoracic and Cardiovascular Surgery 2013 145, 1367-1372DOI: (10.1016/j.jtcvs.2012.07.029) Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions