Phenol Functionalization Inspired by Melanogenesis

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Presentation transcript:

Phenol Functionalization Inspired by Melanogenesis Kenneth Virgel N. Esguerra Chem Volume 2, Issue 4, Pages 451-453 (April 2017) DOI: 10.1016/j.chempr.2017.03.013 Copyright © 2017 Terms and Conditions

Scheme 1 Co-opting Melanogenesis for Low-Energy, Eco-friendly C–N Cross-Coupling (A) Tyrosinase-mediated dual C–N and C–O functionalization of phenols. (B) Catalytic C–H amination using traditional C–H functionalization. (C) Bio-inspired catalytic aerobic functionalization of phenols. (D) Lysyl-oxidase-mediated deamination of lysine. (E) Bio-inspired C–H ortho-amination of phenols. Chem 2017 2, 451-453DOI: (10.1016/j.chempr.2017.03.013) Copyright © 2017 Terms and Conditions

Chem 2017 2, 451-453DOI: (10.1016/j.chempr.2017.03.013) Copyright © 2017 Terms and Conditions